Frequency of In-Stent Restenosis among Different 2nd/3rd Drug Eluting Stents in Patients Presenting with ACS/Angina at Trtiary Cradiac Care Centre
Objective: Primary objective was to determine the frequency of in-stent restenosis (ISR) among second/third generation drug eluting stents (DES), diagnosed angiographically in cardiac catheterization laboratory either in emergency settings or elective stage procedure and to determine the risk facto...
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Army Medical College Rawalpindi
2022-11-01
|
| Series: | Pakistan Armed Forces Medical Journal |
| Subjects: | |
| Online Access: | https://pafmj.org/index.php/PAFMJ/article/view/9541 |
| _version_ | 1797938557557407744 |
|---|---|
| author | Shakir Ghaffar Waheed-Ur- Rehman Alam Khan Muhammad Amad Abbasi Sajjad Ali Muhammad Naeem Tariq Zeeshan Arif Syed Khurram Shahzad Javeria Kamran |
| author_facet | Shakir Ghaffar Waheed-Ur- Rehman Alam Khan Muhammad Amad Abbasi Sajjad Ali Muhammad Naeem Tariq Zeeshan Arif Syed Khurram Shahzad Javeria Kamran |
| author_sort | Shakir Ghaffar |
| collection | DOAJ |
| description |
Objective: Primary objective was to determine the frequency of in-stent restenosis (ISR) among second/third generation drug eluting stents (DES), diagnosed angiographically in cardiac catheterization laboratory either in emergency settings or elective stage procedure and to determine the risk factors precipitating ISR.
Study Design: Analytical Cross-sectional study.
Place and Duration of the study: Tertiary Cardiac Care Center of Rawalpindi Pakistan, from Nov 2021 to Apr 2022.
Methodology: After hospital ethical committee approval, medical data of consecutive patients were analyzed. Clinical and bio data were obtained followed by admission. Risk factors for atherosclerosis obtained along with baseline investigations and echocardiogram obtained to calculate ejection fraction. Classified interventional cardiologists analyzed angiographic images and confirmed the presence of ISR. Details of previous angioplasty and type of stent were documented.
Results: Out of total 137 patients, 98(72%) were males and 39(28%) females. 94(68%) patients were diabetic, 102(72%) were hypertensive, 72(52%) had dyslipidemia, 56(40%) were smokers, and 32(23.35%) strong family history of CHD. After coronary angiography we found that frequency of ISR was 32(23%) in patients who had Xlimus sirolimus stent, 34(24.8%) patients had Xience (everolimus eluting stent), 33(24%) had Ultimaster (sirolimus eluting stent), 38(27%) had Biomatrix stent with p-value=0.25.
Conclusion: The clinical presentation of ISR is usually with angina in all new generation DES. There was no statistically significant difference in terms of ISR among second/3rd generation DES. DES ISR not only depends upon the type of DES used but also depends upon multiple patient ...
|
| first_indexed | 2024-04-10T19:01:35Z |
| format | Article |
| id | doaj.art-c44e95a72b034626894519f60bf47a20 |
| institution | Directory Open Access Journal |
| issn | 0030-9648 2411-8842 |
| language | English |
| last_indexed | 2024-04-10T19:01:35Z |
| publishDate | 2022-11-01 |
| publisher | Army Medical College Rawalpindi |
| record_format | Article |
| series | Pakistan Armed Forces Medical Journal |
| spelling | doaj.art-c44e95a72b034626894519f60bf47a202023-01-31T08:23:06ZengArmy Medical College RawalpindiPakistan Armed Forces Medical Journal0030-96482411-88422022-11-0172SUPPL-310.51253/pafmj.v72iSUPPL-3.9541Frequency of In-Stent Restenosis among Different 2nd/3rd Drug Eluting Stents in Patients Presenting with ACS/Angina at Trtiary Cradiac Care CentreShakir Ghaffar0Waheed-Ur- Rehman1Alam Khan2Muhammad Amad Abbasi3Sajjad Ali4Muhammad Naeem Tariq5Zeeshan Arif6Syed Khurram Shahzad7Javeria Kamran8Armed Forces Institute of Cardiology/National Institute of Heart Diseases (AFIC/NIHD)/National University of Medical Sciences (NUMS) Rawalpindi PakistanArmed Forces Institute of Cardiology/National Institute of Heart Diseases (AFIC/NIHD)/National University of Medical Sciences (NUMS) Rawalpindi PakistanArmed Forces Institute of Cardiology/National Institute of Heart Diseases (AFIC/NIHD)/National University of Medical Sciences (NUMS) Rawalpindi PakistanArmed Forces Institute of Cardiology/National Institute of Heart Diseases (AFIC/NIHD)/National University of Medical Sciences (NUMS) Rawalpindi PakistanArmed Forces Institute of Cardiology/National Institute of Heart Diseases (AFIC/NIHD)/National University of Medical Sciences (NUMS) Rawalpindi PakistanArmed Forces Institute of Cardiology/National Institute of Heart Diseases (AFIC/NIHD)/National University of Medical Sciences (NUMS) Rawalpindi PakistanArmed Forces Institute of Cardiology/National Institute of Heart Diseases (AFIC/NIHD)/National University of Medical Sciences (NUMS) Rawalpindi PakistanArmed Forces Institute of Cardiology/National Institute of Heart Diseases (AFIC/NIHD)/National University of Medical Sciences (NUMS) Rawalpindi PakistanArmed Forces Institute of Cardiology/National Institute of Heart Diseases (AFIC/NIHD)/National University of Medical Sciences (NUMS) Rawalpindi Pakistan Objective: Primary objective was to determine the frequency of in-stent restenosis (ISR) among second/third generation drug eluting stents (DES), diagnosed angiographically in cardiac catheterization laboratory either in emergency settings or elective stage procedure and to determine the risk factors precipitating ISR. Study Design: Analytical Cross-sectional study. Place and Duration of the study: Tertiary Cardiac Care Center of Rawalpindi Pakistan, from Nov 2021 to Apr 2022. Methodology: After hospital ethical committee approval, medical data of consecutive patients were analyzed. Clinical and bio data were obtained followed by admission. Risk factors for atherosclerosis obtained along with baseline investigations and echocardiogram obtained to calculate ejection fraction. Classified interventional cardiologists analyzed angiographic images and confirmed the presence of ISR. Details of previous angioplasty and type of stent were documented. Results: Out of total 137 patients, 98(72%) were males and 39(28%) females. 94(68%) patients were diabetic, 102(72%) were hypertensive, 72(52%) had dyslipidemia, 56(40%) were smokers, and 32(23.35%) strong family history of CHD. After coronary angiography we found that frequency of ISR was 32(23%) in patients who had Xlimus sirolimus stent, 34(24.8%) patients had Xience (everolimus eluting stent), 33(24%) had Ultimaster (sirolimus eluting stent), 38(27%) had Biomatrix stent with p-value=0.25. Conclusion: The clinical presentation of ISR is usually with angina in all new generation DES. There was no statistically significant difference in terms of ISR among second/3rd generation DES. DES ISR not only depends upon the type of DES used but also depends upon multiple patient ... https://pafmj.org/index.php/PAFMJ/article/view/9541Bare metal stentsDrug eluting stentsPercutaneous coronary intervention |
| spellingShingle | Shakir Ghaffar Waheed-Ur- Rehman Alam Khan Muhammad Amad Abbasi Sajjad Ali Muhammad Naeem Tariq Zeeshan Arif Syed Khurram Shahzad Javeria Kamran Frequency of In-Stent Restenosis among Different 2nd/3rd Drug Eluting Stents in Patients Presenting with ACS/Angina at Trtiary Cradiac Care Centre Pakistan Armed Forces Medical Journal Bare metal stents Drug eluting stents Percutaneous coronary intervention |
| title | Frequency of In-Stent Restenosis among Different 2nd/3rd Drug Eluting Stents in Patients Presenting with ACS/Angina at Trtiary Cradiac Care Centre |
| title_full | Frequency of In-Stent Restenosis among Different 2nd/3rd Drug Eluting Stents in Patients Presenting with ACS/Angina at Trtiary Cradiac Care Centre |
| title_fullStr | Frequency of In-Stent Restenosis among Different 2nd/3rd Drug Eluting Stents in Patients Presenting with ACS/Angina at Trtiary Cradiac Care Centre |
| title_full_unstemmed | Frequency of In-Stent Restenosis among Different 2nd/3rd Drug Eluting Stents in Patients Presenting with ACS/Angina at Trtiary Cradiac Care Centre |
| title_short | Frequency of In-Stent Restenosis among Different 2nd/3rd Drug Eluting Stents in Patients Presenting with ACS/Angina at Trtiary Cradiac Care Centre |
| title_sort | frequency of in stent restenosis among different 2nd 3rd drug eluting stents in patients presenting with acs angina at trtiary cradiac care centre |
| topic | Bare metal stents Drug eluting stents Percutaneous coronary intervention |
| url | https://pafmj.org/index.php/PAFMJ/article/view/9541 |
| work_keys_str_mv | AT shakirghaffar frequencyofinstentrestenosisamongdifferent2nd3rddrugelutingstentsinpatientspresentingwithacsanginaattrtiarycradiaccarecentre AT waheedurrehman frequencyofinstentrestenosisamongdifferent2nd3rddrugelutingstentsinpatientspresentingwithacsanginaattrtiarycradiaccarecentre AT alamkhan frequencyofinstentrestenosisamongdifferent2nd3rddrugelutingstentsinpatientspresentingwithacsanginaattrtiarycradiaccarecentre AT muhammadamadabbasi frequencyofinstentrestenosisamongdifferent2nd3rddrugelutingstentsinpatientspresentingwithacsanginaattrtiarycradiaccarecentre AT sajjadali frequencyofinstentrestenosisamongdifferent2nd3rddrugelutingstentsinpatientspresentingwithacsanginaattrtiarycradiaccarecentre AT muhammadnaeemtariq frequencyofinstentrestenosisamongdifferent2nd3rddrugelutingstentsinpatientspresentingwithacsanginaattrtiarycradiaccarecentre AT zeeshanarif frequencyofinstentrestenosisamongdifferent2nd3rddrugelutingstentsinpatientspresentingwithacsanginaattrtiarycradiaccarecentre AT syedkhurramshahzad frequencyofinstentrestenosisamongdifferent2nd3rddrugelutingstentsinpatientspresentingwithacsanginaattrtiarycradiaccarecentre AT javeriakamran frequencyofinstentrestenosisamongdifferent2nd3rddrugelutingstentsinpatientspresentingwithacsanginaattrtiarycradiaccarecentre |