| Summary: | The title compound, C12H16N4O3S·H2O, which has potential as a possible antimalarial drug, was studied when small deviations in melting points, for two differently aged preparations, were observed. The unexpected existence of a water molecule of crystallization is considered to be the cause of this variation. The 7H-pyrrolo[2,3-d]pyrimidine unit is very slightly puckered with a total puckering amplitude of 0.035 (2) Å; its mean plane makes an angle of 88.40 (12)° with the mean plane through the ribofuranosyl unit. In the crystal, the molecules are bound by strong O—H...N and N—H...O hydrogen bonds, utilizing all available protons and linking mainly through the water of crystallization.
|
|---|