Is delayed gastric emptying associated with pylorus ring preservation in patients undergoing pancreaticoduodenectomy?
Background/objective: A high incidence of delayed gastric emptying (DGE) is observed in patients undergoing pylorus-preserving pancreaticoduodenectomy (PpPD). However, DGE incidence after pancreaticoduodenectomy varied because of heterogeneity in surgical techniques, number of surgeons, and DGE defi...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2021-01-01
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| Series: | Asian Journal of Surgery |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1015958420302591 |
| _version_ | 1818970296832491520 |
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| author | Yun Ho Lee Young Hoe Hur Hee Joon Kim Choong Young Kim Jin Woong Kim |
| author_facet | Yun Ho Lee Young Hoe Hur Hee Joon Kim Choong Young Kim Jin Woong Kim |
| author_sort | Yun Ho Lee |
| collection | DOAJ |
| description | Background/objective: A high incidence of delayed gastric emptying (DGE) is observed in patients undergoing pylorus-preserving pancreaticoduodenectomy (PpPD). However, DGE incidence after pancreaticoduodenectomy varied because of heterogeneity in surgical techniques, number of surgeons, and DGE definition. This study aimed to evaluate the difference in the incidence of DGE following PpPD and pylorus-resecting pancreaticoduodenectomy (PrPD) and to analyze the risk factor of DGE by a single surgeon to determine whether pylorus preservation was the main factor of DGE. Methods: This retrospective study included 115 patients who underwent PpPD (with pylorus ring preservation) and PrPD (without pylorus ring preservation) with laparotomy by a single surgeon at a tertiary center. Results: The overall incidence of DGE was 23.1%. For comparison, 20 patients (39.2%) in the PpPD group and 5 patients (8.8%) in the PrPD group had DGE, showing a significant difference (p < 0.001). On univariate analysis, hypertension, PpPD, operation time, intraoperative bleeding, packed red blood cell transfusion ≥500 mL, and clinically relevant postoperative pancreatic fistula were associated with DGE. Multivariate analysis identified pylorus preservation and clinically relevant postoperative pancreatic fistula as risk factors for DGE. Conclusion: Compared with PpPD, PrPD significantly reduced the incidence of DGE. |
| first_indexed | 2024-12-20T14:34:14Z |
| format | Article |
| id | doaj.art-c452f60baf0a4deda96a5c4c6423970a |
| institution | Directory Open Access Journal |
| issn | 1015-9584 |
| language | English |
| last_indexed | 2024-12-20T14:34:14Z |
| publishDate | 2021-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Asian Journal of Surgery |
| spelling | doaj.art-c452f60baf0a4deda96a5c4c6423970a2022-12-21T19:37:31ZengElsevierAsian Journal of Surgery1015-95842021-01-01441137142Is delayed gastric emptying associated with pylorus ring preservation in patients undergoing pancreaticoduodenectomy?Yun Ho Lee0Young Hoe Hur1Hee Joon Kim2Choong Young Kim3Jin Woong Kim4Department of Surgery, Chonnam National University Hwasun Hospital and Medical School, Hwasun, South KoreaDepartment of Surgery, Chonnam National University Hwasun Hospital and Medical School, Hwasun, South Korea; Corresponding author. Department of Surgery, Chonnam National University Hwasun Hospital and Medical School, 322 Seoyang-ro, Chonnam, 58128, South Korea.Department of Surgery, Chonnam National University Hospital and Medical School, Gwangju, South KoreaDepartment of Surgery, Chonnam National University Hwasun Hospital and Medical School, Hwasun, South KoreaDepartment of Radiology, Chosun University Hospital and Chosun University College of Medicine, Gwangju, South KoreaBackground/objective: A high incidence of delayed gastric emptying (DGE) is observed in patients undergoing pylorus-preserving pancreaticoduodenectomy (PpPD). However, DGE incidence after pancreaticoduodenectomy varied because of heterogeneity in surgical techniques, number of surgeons, and DGE definition. This study aimed to evaluate the difference in the incidence of DGE following PpPD and pylorus-resecting pancreaticoduodenectomy (PrPD) and to analyze the risk factor of DGE by a single surgeon to determine whether pylorus preservation was the main factor of DGE. Methods: This retrospective study included 115 patients who underwent PpPD (with pylorus ring preservation) and PrPD (without pylorus ring preservation) with laparotomy by a single surgeon at a tertiary center. Results: The overall incidence of DGE was 23.1%. For comparison, 20 patients (39.2%) in the PpPD group and 5 patients (8.8%) in the PrPD group had DGE, showing a significant difference (p < 0.001). On univariate analysis, hypertension, PpPD, operation time, intraoperative bleeding, packed red blood cell transfusion ≥500 mL, and clinically relevant postoperative pancreatic fistula were associated with DGE. Multivariate analysis identified pylorus preservation and clinically relevant postoperative pancreatic fistula as risk factors for DGE. Conclusion: Compared with PpPD, PrPD significantly reduced the incidence of DGE.http://www.sciencedirect.com/science/article/pii/S1015958420302591 |
| spellingShingle | Yun Ho Lee Young Hoe Hur Hee Joon Kim Choong Young Kim Jin Woong Kim Is delayed gastric emptying associated with pylorus ring preservation in patients undergoing pancreaticoduodenectomy? Asian Journal of Surgery |
| title | Is delayed gastric emptying associated with pylorus ring preservation in patients undergoing pancreaticoduodenectomy? |
| title_full | Is delayed gastric emptying associated with pylorus ring preservation in patients undergoing pancreaticoduodenectomy? |
| title_fullStr | Is delayed gastric emptying associated with pylorus ring preservation in patients undergoing pancreaticoduodenectomy? |
| title_full_unstemmed | Is delayed gastric emptying associated with pylorus ring preservation in patients undergoing pancreaticoduodenectomy? |
| title_short | Is delayed gastric emptying associated with pylorus ring preservation in patients undergoing pancreaticoduodenectomy? |
| title_sort | is delayed gastric emptying associated with pylorus ring preservation in patients undergoing pancreaticoduodenectomy |
| url | http://www.sciencedirect.com/science/article/pii/S1015958420302591 |
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