DNA origami presenting the receptor binding domain of SARS-CoV-2 elicit robust protective immune response

DNA origami presenting the receptor binding domain of SARS-CoV-2 elicit robust protective immune response

A DNA origami nanoparticle-based vaccine against SARS-Cov-2 co-delivers viral RBD antigen and CpG adjuvant and elicits a robust protective immunity against the virus in a mouse model.

Bibliographic Details
Main Authors: Esra Oktay, Farhang Alem, Keziah Hernandez, Michael Girgis, Christopher Green, Divita Mathur, Igor L. Medintz, Aarthi Narayanan, Remi Veneziano
Format: Article
Language:English
Published: Nature Portfolio 2023-03-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-023-04689-2

Internet

https://doi.org/10.1038/s42003-023-04689-2

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