Crotalic accidents in Brazil: actualities and perspectives

Introduction: Ophidian accidents are neglected events in tropical and in developing countries, including Brazil. Serpents of the Crotalus genus (rattlesnakes) are those that produce the highest case-fatality in the country. Purpose: to address the main aspects of the accident caused by Crotalus,...

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Main Authors: Hammer, Fernanda Martins, Feio, Renato Neves, Siqueira-Batista, Rodrigo
Format: Article
Language:English
Published: Associação Médica de Minas Gerais 2022-03-01
Series:Revista Médica de Minas Gerais
Subjects:
Online Access:http://www.rmmg.org/artigo/detalhes/3882
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author Hammer, Fernanda Martins
Feio, Renato Neves
Siqueira-Batista, Rodrigo
author_facet Hammer, Fernanda Martins
Feio, Renato Neves
Siqueira-Batista, Rodrigo
author_sort Hammer, Fernanda Martins
collection DOAJ
description Introduction: Ophidian accidents are neglected events in tropical and in developing countries, including Brazil. Serpents of the Crotalus genus (rattlesnakes) are those that produce the highest case-fatality in the country. Purpose: to address the main aspects of the accident caused by Crotalus, with emphasis on the snakes biology, the clinical approach to snake bites and the therapeutic properties of the venom of these animals. Methods: literature review with a defined search strategy, using the PubMed, LILACS and SciELO databases. Results: Inoculation of crotalic venom produces discrete local signs, but systemic repercussions can occur, especially neurological alterations and acute renal failure. Laboratory evaluation is important to help distinguish from other ophidian accidents and to estimate the severity of the condition. Anticrotalic serum must be administered as soon as possible, based on the estimated amount of inoculated venom. Most of the morbid events occur in the rainy season (higher temperature), mainly affecting young men who work in rural areas. The adoption of protective measures and health education, aimed at the population most commonly involved, are relevant strategies for preventing and reducing the number of cases. In addition, crotalic venoms have antimicrobial actions, antiplatelets functions and ophthalmological applicability (strabismus). Conclusion: Knowledge of the different aspects of crotalic injuries is essential for an adequate diagnostic and therapeutic approach to such morbid conditions. The pharmacological properties of crotalic venom components should be better investigated in the next few years, given the possibilities of their use for the treatment of different human diseases.
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spelling doaj.art-c459b59623094f358ee62853ed8d20a12022-12-22T01:53:58ZengAssociação Médica de Minas GeraisRevista Médica de Minas Gerais0103-880X2238-31822022-03-0132e-3220210.5935/2238-3182.2022e32202Crotalic accidents in Brazil: actualities and perspectivesHammer, Fernanda Martins0https://orcid.org/0000-0002-6289-4930Feio, Renato Neves1https://orcid.org/0000-0002-3607-2896Siqueira-Batista, Rodrigo 2https://orcid.org/0000-0002-3661-1570Faculdade Dinâmica do Vale do Piranga, Ponte Nova, Minas Gerais, Brasil.Universidade Federal de Viçosa, Viçosa, Minas Gerais, BrasilFaculdade Dinâmica do Vale do Piranga, Ponte Nova, Minas Gerais, Brasil / Universidade Federal de Viçosa, Viçosa, Minas Gerais, BrasilIntroduction: Ophidian accidents are neglected events in tropical and in developing countries, including Brazil. Serpents of the Crotalus genus (rattlesnakes) are those that produce the highest case-fatality in the country. Purpose: to address the main aspects of the accident caused by Crotalus, with emphasis on the snakes biology, the clinical approach to snake bites and the therapeutic properties of the venom of these animals. Methods: literature review with a defined search strategy, using the PubMed, LILACS and SciELO databases. Results: Inoculation of crotalic venom produces discrete local signs, but systemic repercussions can occur, especially neurological alterations and acute renal failure. Laboratory evaluation is important to help distinguish from other ophidian accidents and to estimate the severity of the condition. Anticrotalic serum must be administered as soon as possible, based on the estimated amount of inoculated venom. Most of the morbid events occur in the rainy season (higher temperature), mainly affecting young men who work in rural areas. The adoption of protective measures and health education, aimed at the population most commonly involved, are relevant strategies for preventing and reducing the number of cases. In addition, crotalic venoms have antimicrobial actions, antiplatelets functions and ophthalmological applicability (strabismus). Conclusion: Knowledge of the different aspects of crotalic injuries is essential for an adequate diagnostic and therapeutic approach to such morbid conditions. The pharmacological properties of crotalic venom components should be better investigated in the next few years, given the possibilities of their use for the treatment of different human diseases.http://www.rmmg.org/artigo/detalhes/3882crotalusrattlesnakecrotoxin
spellingShingle Hammer, Fernanda Martins
Feio, Renato Neves
Siqueira-Batista, Rodrigo
Crotalic accidents in Brazil: actualities and perspectives
Revista Médica de Minas Gerais
crotalus
rattlesnake
crotoxin
title Crotalic accidents in Brazil: actualities and perspectives
title_full Crotalic accidents in Brazil: actualities and perspectives
title_fullStr Crotalic accidents in Brazil: actualities and perspectives
title_full_unstemmed Crotalic accidents in Brazil: actualities and perspectives
title_short Crotalic accidents in Brazil: actualities and perspectives
title_sort crotalic accidents in brazil actualities and perspectives
topic crotalus
rattlesnake
crotoxin
url http://www.rmmg.org/artigo/detalhes/3882
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