cis-Expression QTL analysis of established colorectal cancer risk variants in colon tumors and adjacent normal tissue.

cis-Expression QTL analysis of established colorectal cancer risk variants in colon tumors and adjacent normal tissue.

Genome-wide association studies (GWAS) have identified 19 risk variants associated with colorectal cancer. As most of these risk variants reside outside the coding regions of genes, we conducted cis-expression quantitative trait loci (cis-eQTL) analyses to investigate possible regulatory functions o...

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Bibliographic Details
Main Authors: Lenora W M Loo, Iona Cheng, Maarit Tiirikainen, Annette Lum-Jones, Ann Seifried, Lucas M Dunklee, James M Church, Robert Gryfe, Daniel J Weisenberger, Robert W Haile, Steven Gallinger, David J Duggan, Stephen N Thibodeau, Graham Casey, Loïc Le Marchand
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3281844?pdf=render

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