Experimental and Clinical Evidence Suggests That Treatment with Betacellulin Can Alleviate Th2-Type Cytokine-Mediated Impairment of Skin Barrier Function

Experimental and Clinical Evidence Suggests That Treatment with Betacellulin Can Alleviate Th2-Type Cytokine-Mediated Impairment of Skin Barrier Function

Betacellulin (BTC) is a peptide ligand that belongs to the epidermal growth factor family, the members of which have been implicated in skin morphogenesis, homeostasis, repair, and angiogenesis; however, the role of BTC in the regulation of the skin barrier remains unknown. To examine the role of BT...

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Bibliographic Details
Main Authors: Ge Peng, Saya Tsukamoto, Yoshie Umehara, Ryoma Kishi, Mitsutoshi Tominaga, Kenji Takamori, Ko Okumura, Hideoki Ogawa, Shigaku Ikeda, François Niyonsaba
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:International Journal of Molecular Sciences
Subjects:
betacellulin
atopic dermatitis
biomarker
keratinocyte
skin barrier
Online Access:https://www.mdpi.com/1422-0067/23/19/11520

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