Involvement of S100A8/A9-TLR4-NLRP3 Inflammasome Pathway in Contrast-Induced Acute Kidney Injury

Involvement of S100A8/A9-TLR4-NLRP3 Inflammasome Pathway in Contrast-Induced Acute Kidney Injury

Background: Contrast-induced acute kidney injury (CIAKI) is a common cause of hospital-acquired acute kidney injury (AKI). S100A8/A9-TLR4-NLRP3 inflammasome pathway triggers inflammation, apoptosis and tissue injury in several AKI models. Nevertheless, the underlying mechanism of S100A8/A9-TLR4-NLRP...

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Bibliographic Details
Main Authors: Xuexian Tan, Xiaohe Zheng, Zena Huang, Jiaqiong Lin, Chuli Xie, Yan Lin
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2017-08-01
Series:Cellular Physiology and Biochemistry
Subjects:
S100A8/A9
TLR4
NLRP3 inflammasome
Contrast medium
Acute kidney injury
Online Access:http://www.karger.com/Article/FullText/480340

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