Symmetry (Asymmetry) of the Molar Excess Gibbs Free Energy Function of the Binary Mixed Micelles of Bile Acid Anion and Classical Cationic Surfactant: Influence of Sterically Shielded and Sterically Unshielded Polar Groups of the Steroid Skeleton
Binary mixtures of surfactants build a binary mixed micelle in which the ratio of surfactants usually differs from the initial ratio of surfactants in their binary mixture. The thermodynamic stabilization of the binary mixed micellar pseudophase about the hypothetical ideal state (intermolecular int...
| Main Author: | |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2022-11-01
|
| Series: | Symmetry |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2073-8994/14/11/2337 |
| _version_ | 1797466411011932160 |
|---|---|
| author | Mihalj Poša |
| author_facet | Mihalj Poša |
| author_sort | Mihalj Poša |
| collection | DOAJ |
| description | Binary mixtures of surfactants build a binary mixed micelle in which the ratio of surfactants usually differs from the initial ratio of surfactants in their binary mixture. The thermodynamic stabilization of the binary mixed micellar pseudophase about the hypothetical ideal state (intermolecular interactions between the different particles and the conformational states of the particles are identical to those of monocomponent states) is described by the molar excess Gibbs free energy (<i>g<sup>E</sup></i>). The dependence of <i>g<sup>E</sup></i> on the molar fraction of surfactant <i>i</i> (<i>x<sub>i</sub></i>) from the binary mixed micelle can be described by a symmetric function (symmetry is described to the line parallel to the y-axis and passes through <i>x<sub>i</sub></i> = 0.5) or by an asymmetric function. Theoretical analysis (canonical partition function, conformational analysis) examines how the presence of different polar functional groups, some of which are sterically shielded from the steroid skeleton of bile salts (surfactant), affect the symmetry of the function <i>g<sup>E</sup></i> of the binary mixed micelle of the cholic acid anion (bile salts) and classic cationic surfactant (hydrophobic tail and polar head). Suppose the steroid skeleton of the bile salt contains non-sterically shielded polar groups (or the temperature is relatively high). In that case, <i>g<sup>E</sup></i> is a symmetric function. At the same time, if the steroid skeleton also contains sterically shielded polar groups, then the <i>g<sup>E</sup></i> function is asymmetric. |
| first_indexed | 2024-03-09T18:36:32Z |
| format | Article |
| id | doaj.art-c46b685483b74be1aa8e4daf5ae6c91e |
| institution | Directory Open Access Journal |
| issn | 2073-8994 |
| language | English |
| last_indexed | 2024-03-09T18:36:32Z |
| publishDate | 2022-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Symmetry |
| spelling | doaj.art-c46b685483b74be1aa8e4daf5ae6c91e2023-11-24T07:08:42ZengMDPI AGSymmetry2073-89942022-11-011411233710.3390/sym14112337Symmetry (Asymmetry) of the Molar Excess Gibbs Free Energy Function of the Binary Mixed Micelles of Bile Acid Anion and Classical Cationic Surfactant: Influence of Sterically Shielded and Sterically Unshielded Polar Groups of the Steroid SkeletonMihalj Poša0Department of Pharmacy, Faculty of Medicine, University of Novi Sad, Hajduk Veljka 3, 21000 Novi Sad, SerbiaBinary mixtures of surfactants build a binary mixed micelle in which the ratio of surfactants usually differs from the initial ratio of surfactants in their binary mixture. The thermodynamic stabilization of the binary mixed micellar pseudophase about the hypothetical ideal state (intermolecular interactions between the different particles and the conformational states of the particles are identical to those of monocomponent states) is described by the molar excess Gibbs free energy (<i>g<sup>E</sup></i>). The dependence of <i>g<sup>E</sup></i> on the molar fraction of surfactant <i>i</i> (<i>x<sub>i</sub></i>) from the binary mixed micelle can be described by a symmetric function (symmetry is described to the line parallel to the y-axis and passes through <i>x<sub>i</sub></i> = 0.5) or by an asymmetric function. Theoretical analysis (canonical partition function, conformational analysis) examines how the presence of different polar functional groups, some of which are sterically shielded from the steroid skeleton of bile salts (surfactant), affect the symmetry of the function <i>g<sup>E</sup></i> of the binary mixed micelle of the cholic acid anion (bile salts) and classic cationic surfactant (hydrophobic tail and polar head). Suppose the steroid skeleton of the bile salt contains non-sterically shielded polar groups (or the temperature is relatively high). In that case, <i>g<sup>E</sup></i> is a symmetric function. At the same time, if the steroid skeleton also contains sterically shielded polar groups, then the <i>g<sup>E</sup></i> function is asymmetric.https://www.mdpi.com/2073-8994/14/11/2337conformationsteroid skeletonsurfactantsmixed micellesbile saltsregular solution theory |
| spellingShingle | Mihalj Poša Symmetry (Asymmetry) of the Molar Excess Gibbs Free Energy Function of the Binary Mixed Micelles of Bile Acid Anion and Classical Cationic Surfactant: Influence of Sterically Shielded and Sterically Unshielded Polar Groups of the Steroid Skeleton Symmetry conformation steroid skeleton surfactants mixed micelles bile salts regular solution theory |
| title | Symmetry (Asymmetry) of the Molar Excess Gibbs Free Energy Function of the Binary Mixed Micelles of Bile Acid Anion and Classical Cationic Surfactant: Influence of Sterically Shielded and Sterically Unshielded Polar Groups of the Steroid Skeleton |
| title_full | Symmetry (Asymmetry) of the Molar Excess Gibbs Free Energy Function of the Binary Mixed Micelles of Bile Acid Anion and Classical Cationic Surfactant: Influence of Sterically Shielded and Sterically Unshielded Polar Groups of the Steroid Skeleton |
| title_fullStr | Symmetry (Asymmetry) of the Molar Excess Gibbs Free Energy Function of the Binary Mixed Micelles of Bile Acid Anion and Classical Cationic Surfactant: Influence of Sterically Shielded and Sterically Unshielded Polar Groups of the Steroid Skeleton |
| title_full_unstemmed | Symmetry (Asymmetry) of the Molar Excess Gibbs Free Energy Function of the Binary Mixed Micelles of Bile Acid Anion and Classical Cationic Surfactant: Influence of Sterically Shielded and Sterically Unshielded Polar Groups of the Steroid Skeleton |
| title_short | Symmetry (Asymmetry) of the Molar Excess Gibbs Free Energy Function of the Binary Mixed Micelles of Bile Acid Anion and Classical Cationic Surfactant: Influence of Sterically Shielded and Sterically Unshielded Polar Groups of the Steroid Skeleton |
| title_sort | symmetry asymmetry of the molar excess gibbs free energy function of the binary mixed micelles of bile acid anion and classical cationic surfactant influence of sterically shielded and sterically unshielded polar groups of the steroid skeleton |
| topic | conformation steroid skeleton surfactants mixed micelles bile salts regular solution theory |
| url | https://www.mdpi.com/2073-8994/14/11/2337 |
| work_keys_str_mv | AT mihaljposa symmetryasymmetryofthemolarexcessgibbsfreeenergyfunctionofthebinarymixedmicellesofbileacidanionandclassicalcationicsurfactantinfluenceofstericallyshieldedandstericallyunshieldedpolargroupsofthesteroidskeleton |