Rapid and efficient characterization of cervical collagen orientation using linearly polarized colposcopic images
Collagen provides tissue strength and structural integrity. Quantification of the orientated dispersion of collagen fibers is an important factor when studying the mechanical properties of the cervix. In this study, for the first time, a new method for rapid characterization of the collagen fiber or...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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World Scientific Publishing
2023-09-01
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| Series: | Journal of Innovative Optical Health Sciences |
| Subjects: | |
| Online Access: | https://www.worldscientific.com/doi/10.1142/S1793545822410012 |
| _version_ | 1797685192281817088 |
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| author | Cat Phan Ngoc Khuong Dung Nguyen Huu Quang Hai Pham Thanh Long Nguyen Quynh Nguyen Ngoc Duc Le Huynh Tien Tran Van Tu Ly Anh |
| author_facet | Cat Phan Ngoc Khuong Dung Nguyen Huu Quang Hai Pham Thanh Long Nguyen Quynh Nguyen Ngoc Duc Le Huynh Tien Tran Van Tu Ly Anh |
| author_sort | Cat Phan Ngoc Khuong |
| collection | DOAJ |
| description | Collagen provides tissue strength and structural integrity. Quantification of the orientated dispersion of collagen fibers is an important factor when studying the mechanical properties of the cervix. In this study, for the first time, a new method for rapid characterization of the collagen fiber orientations of the cervix using linearly polarized light colposcopy is presented. A total of 24 colposcopic images were captured using a cross-polarized imaging system with white LED light sources. In the preprocessing stage, the Red channel of the RGB image was chosen, which contains no information of the blood vessels because of the low-absorption of blood cells in the red region. OrientationJ, which is an ImageJ plug-in, was used to estimate the local orientation of the collagen fibers. The result shows that in the nonpregnant cervix, the middle zone (Zone 2) has circumferentially aligned collagen fibers while the inner zone (Zone 1) has randomly arranged. The collagen fiber dispersion in Zone 2 is much smaller than that in Zone 1 at all four quadrants region (anterior, posterior, left, and right quadrant). This new analysis technique could potentially combine with diagnostic tools to provide a quantitative platform of collagen fibers in the clinic. |
| first_indexed | 2024-03-12T00:40:37Z |
| format | Article |
| id | doaj.art-c46bc3ebeddd4f91b9092da910ac9d59 |
| institution | Directory Open Access Journal |
| issn | 1793-5458 1793-7205 |
| language | English |
| last_indexed | 2024-03-12T00:40:37Z |
| publishDate | 2023-09-01 |
| publisher | World Scientific Publishing |
| record_format | Article |
| series | Journal of Innovative Optical Health Sciences |
| spelling | doaj.art-c46bc3ebeddd4f91b9092da910ac9d592023-09-15T08:16:34ZengWorld Scientific PublishingJournal of Innovative Optical Health Sciences1793-54581793-72052023-09-01160510.1142/S1793545822410012Rapid and efficient characterization of cervical collagen orientation using linearly polarized colposcopic imagesCat Phan Ngoc Khuong0Dung Nguyen Huu Quang1Hai Pham Thanh2Long Nguyen3Quynh Nguyen Ngoc4Duc Le Huynh5Tien Tran Van6Tu Ly Anh7Department of Applied Physics, Ho Chi Minh City University of Technology, 268 Ly Thuong Kiet Street, District 10, Ho Chi Minh City 700 000, VietnamDepartment of Applied Physics, Ho Chi Minh City University of Technology, 268 Ly Thuong Kiet Street, District 10, Ho Chi Minh City 700 000, VietnamQuality Management Department, Tu Du Hospital, 284 Cong Quynh, District 1, Ho Chi Minh City 700 000, VietnamQuality Management Department, Tu Du Hospital, 284 Cong Quynh, District 1, Ho Chi Minh City 700 000, VietnamDepartment of Biomedical Engineering, Nguyen Tat Thanh University, 300A Nguyen Tat Thanh, District 4, Ho Chi Minh City 700 000, VietnamFaculty of Science and Technology, Jean Monnet University, 11 Rue du Docteur Annino, Saint Etienne 42000, FranceDepartment of Applied Physics, Ho Chi Minh City University of Technology, 268 Ly Thuong Kiet Street, District 10, Ho Chi Minh City 700 000, VietnamDepartment of Applied Physics, Ho Chi Minh City University of Technology, 268 Ly Thuong Kiet Street, District 10, Ho Chi Minh City 700 000, VietnamCollagen provides tissue strength and structural integrity. Quantification of the orientated dispersion of collagen fibers is an important factor when studying the mechanical properties of the cervix. In this study, for the first time, a new method for rapid characterization of the collagen fiber orientations of the cervix using linearly polarized light colposcopy is presented. A total of 24 colposcopic images were captured using a cross-polarized imaging system with white LED light sources. In the preprocessing stage, the Red channel of the RGB image was chosen, which contains no information of the blood vessels because of the low-absorption of blood cells in the red region. OrientationJ, which is an ImageJ plug-in, was used to estimate the local orientation of the collagen fibers. The result shows that in the nonpregnant cervix, the middle zone (Zone 2) has circumferentially aligned collagen fibers while the inner zone (Zone 1) has randomly arranged. The collagen fiber dispersion in Zone 2 is much smaller than that in Zone 1 at all four quadrants region (anterior, posterior, left, and right quadrant). This new analysis technique could potentially combine with diagnostic tools to provide a quantitative platform of collagen fibers in the clinic.https://www.worldscientific.com/doi/10.1142/S1793545822410012Cervixcollagen fiberscollagen orientationcoherencycross-polarized imagingcolposcopy |
| spellingShingle | Cat Phan Ngoc Khuong Dung Nguyen Huu Quang Hai Pham Thanh Long Nguyen Quynh Nguyen Ngoc Duc Le Huynh Tien Tran Van Tu Ly Anh Rapid and efficient characterization of cervical collagen orientation using linearly polarized colposcopic images Journal of Innovative Optical Health Sciences Cervix collagen fibers collagen orientation coherency cross-polarized imaging colposcopy |
| title | Rapid and efficient characterization of cervical collagen orientation using linearly polarized colposcopic images |
| title_full | Rapid and efficient characterization of cervical collagen orientation using linearly polarized colposcopic images |
| title_fullStr | Rapid and efficient characterization of cervical collagen orientation using linearly polarized colposcopic images |
| title_full_unstemmed | Rapid and efficient characterization of cervical collagen orientation using linearly polarized colposcopic images |
| title_short | Rapid and efficient characterization of cervical collagen orientation using linearly polarized colposcopic images |
| title_sort | rapid and efficient characterization of cervical collagen orientation using linearly polarized colposcopic images |
| topic | Cervix collagen fibers collagen orientation coherency cross-polarized imaging colposcopy |
| url | https://www.worldscientific.com/doi/10.1142/S1793545822410012 |
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