Ibuprofen: safety and efficiency of its use in wide clinical practice
The paper presents data on the pharmacokinetics of the nonsteroidal anti-inflammatory drug ibuprofen and a review of the evidence base that suggests its clinical efficacy and safety in different categories of patients and discusses new, potentially possible indications for the use of this drug. Ibup...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | Russian |
| Published: |
"Consilium Medicum" Publishing house
2013-03-01
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| Series: | Терапевтический архив |
| Subjects: | |
| Online Access: | https://ter-arkhiv.ru/0040-3660/article/view/31269 |
| _version_ | 1818314325802090496 |
|---|---|
| author | T E Morozova T B AndruShchishina E K Antipova |
| author_facet | T E Morozova T B AndruShchishina E K Antipova |
| author_sort | T E Morozova |
| collection | DOAJ |
| description | The paper presents data on the pharmacokinetics of the nonsteroidal anti-inflammatory drug ibuprofen and a review of the evidence base that suggests its clinical efficacy and safety in different categories of patients and discusses new, potentially possible indications for the use of this drug. Ibuprofen has marked anti-inflammatory, analgesic, and antipyretic effects, which along with its good tolerability, predictability of side effects, and a low risk of complications, allows it to be widely use in clinical practice. There are various ibuprofen formulations on the drug market. There may be not only an oral formulation of ibuprofen, but its topical (gel), rectal (suppositories), and parenteral (solution for intravenous injection) ones. More than 40 years' experience with ibuprofen used as an over-the-counter drug in wide clinical practice in approximately 80 countries worldwide serves as an illustrative example of the efficacy and safety of this agent. |
| first_indexed | 2024-12-13T08:47:51Z |
| format | Article |
| id | doaj.art-c46ca9042e804082ae37be96af1bd7df |
| institution | Directory Open Access Journal |
| issn | 0040-3660 2309-5342 |
| language | Russian |
| last_indexed | 2024-12-13T08:47:51Z |
| publishDate | 2013-03-01 |
| publisher | "Consilium Medicum" Publishing house |
| record_format | Article |
| series | Терапевтический архив |
| spelling | doaj.art-c46ca9042e804082ae37be96af1bd7df2022-12-21T23:53:26Zrus"Consilium Medicum" Publishing houseТерапевтический архив0040-36602309-53422013-03-0185311812428285Ibuprofen: safety and efficiency of its use in wide clinical practiceT E MorozovaT B AndruShchishinaE K AntipovaThe paper presents data on the pharmacokinetics of the nonsteroidal anti-inflammatory drug ibuprofen and a review of the evidence base that suggests its clinical efficacy and safety in different categories of patients and discusses new, potentially possible indications for the use of this drug. Ibuprofen has marked anti-inflammatory, analgesic, and antipyretic effects, which along with its good tolerability, predictability of side effects, and a low risk of complications, allows it to be widely use in clinical practice. There are various ibuprofen formulations on the drug market. There may be not only an oral formulation of ibuprofen, but its topical (gel), rectal (suppositories), and parenteral (solution for intravenous injection) ones. More than 40 years' experience with ibuprofen used as an over-the-counter drug in wide clinical practice in approximately 80 countries worldwide serves as an illustrative example of the efficacy and safety of this agent.https://ter-arkhiv.ru/0040-3660/article/view/31269nonsteroidal anti-inflammatory drugsover-the-counter drugsibuprofenefficacytoleranceside effectspharmacokinetics of ibuprofendosage forms |
| spellingShingle | T E Morozova T B AndruShchishina E K Antipova Ibuprofen: safety and efficiency of its use in wide clinical practice Терапевтический архив nonsteroidal anti-inflammatory drugs over-the-counter drugs ibuprofen efficacy tolerance side effects pharmacokinetics of ibuprofen dosage forms |
| title | Ibuprofen: safety and efficiency of its use in wide clinical practice |
| title_full | Ibuprofen: safety and efficiency of its use in wide clinical practice |
| title_fullStr | Ibuprofen: safety and efficiency of its use in wide clinical practice |
| title_full_unstemmed | Ibuprofen: safety and efficiency of its use in wide clinical practice |
| title_short | Ibuprofen: safety and efficiency of its use in wide clinical practice |
| title_sort | ibuprofen safety and efficiency of its use in wide clinical practice |
| topic | nonsteroidal anti-inflammatory drugs over-the-counter drugs ibuprofen efficacy tolerance side effects pharmacokinetics of ibuprofen dosage forms |
| url | https://ter-arkhiv.ru/0040-3660/article/view/31269 |
| work_keys_str_mv | AT temorozova ibuprofensafetyandefficiencyofitsuseinwideclinicalpractice AT tbandrushchishina ibuprofensafetyandefficiencyofitsuseinwideclinicalpractice AT ekantipova ibuprofensafetyandefficiencyofitsuseinwideclinicalpractice |