Abordagem actual da gota.

Gout, one of the most prevalent rheumatic diseases in the world, results from deposition of uric acid crystals in several locations, particularly in joints, subcutaneous tissues and kidney. The classical treatments, although effective, are often poorly tolerated or contraindicated. Recently, new dru...

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Main Authors: Cláudia Miguel, Maria Jesús Mediavilla
Format: Article
Language:English
Published: Ordem dos Médicos 2011-12-01
Series:Acta Médica Portuguesa
Online Access:https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/507
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author Cláudia Miguel
Maria Jesús Mediavilla
author_facet Cláudia Miguel
Maria Jesús Mediavilla
author_sort Cláudia Miguel
collection DOAJ
description Gout, one of the most prevalent rheumatic diseases in the world, results from deposition of uric acid crystals in several locations, particularly in joints, subcutaneous tissues and kidney. The classical treatments, although effective, are often poorly tolerated or contraindicated. Recently, new drugs have emerged for the treatment of hyperuricemia and gout, including febuxostat and uricase, which proved to be quite promising. Some drugs already used in other diseases, such as losartan, atorvastatin, fenofibrate and amlodipine also seem to have a role in monitoring the serum uric acid. This article reviews the pathophysiology, clinical management and current therapeutic options for Hyperuricemia and Gout.
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spelling doaj.art-c4701290161848f39e3d1f121ab968b62022-12-22T03:38:31ZengOrdem dos MédicosActa Médica Portuguesa0870-399X1646-07582011-12-0124510.20344/amp.507Abordagem actual da gota.Cláudia Miguel0Maria Jesús MediavillaInstituto Português de Reumatologia, Lisboa, Portugal.Gout, one of the most prevalent rheumatic diseases in the world, results from deposition of uric acid crystals in several locations, particularly in joints, subcutaneous tissues and kidney. The classical treatments, although effective, are often poorly tolerated or contraindicated. Recently, new drugs have emerged for the treatment of hyperuricemia and gout, including febuxostat and uricase, which proved to be quite promising. Some drugs already used in other diseases, such as losartan, atorvastatin, fenofibrate and amlodipine also seem to have a role in monitoring the serum uric acid. This article reviews the pathophysiology, clinical management and current therapeutic options for Hyperuricemia and Gout.https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/507
spellingShingle Cláudia Miguel
Maria Jesús Mediavilla
Abordagem actual da gota.
Acta Médica Portuguesa
title Abordagem actual da gota.
title_full Abordagem actual da gota.
title_fullStr Abordagem actual da gota.
title_full_unstemmed Abordagem actual da gota.
title_short Abordagem actual da gota.
title_sort abordagem actual da gota
url https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/507
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