Enterocytozoon bieneusi Microsporidiosis in Stem Cell Transplant Recipients Treated with Fumagillin

Enterocytozoon bieneusi microsporidiosis is an emerging disease in immunocompromised patients. We report 2 cases of this disease in allogeneic hematopoietic stem cell transplant patients successfully treated with fumagillin. Thrombocytopenia occurred but without major adverse events. Modifications o...

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Main Authors: Iryna Bukreyeva, Adela Angoulvant, Inès Bendib, Jean-Charles Gagnard, Jean-Henri Bourhis, Sylvie Dargère, Julie Bonhomme, Marc Thellier, Bertrand Gachot, Benjamin Wyplosz
Format: Article
Language:English
Published: Centers for Disease Control and Prevention 2017-06-01
Series:Emerging Infectious Diseases
Subjects:
Online Access:https://wwwnc.cdc.gov/eid/article/23/6/16-1825_article
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author Iryna Bukreyeva
Adela Angoulvant
Inès Bendib
Jean-Charles Gagnard
Jean-Henri Bourhis
Sylvie Dargère
Julie Bonhomme
Marc Thellier
Bertrand Gachot
Benjamin Wyplosz
author_facet Iryna Bukreyeva
Adela Angoulvant
Inès Bendib
Jean-Charles Gagnard
Jean-Henri Bourhis
Sylvie Dargère
Julie Bonhomme
Marc Thellier
Bertrand Gachot
Benjamin Wyplosz
author_sort Iryna Bukreyeva
collection DOAJ
description Enterocytozoon bieneusi microsporidiosis is an emerging disease in immunocompromised patients. We report 2 cases of this disease in allogeneic hematopoietic stem cell transplant patients successfully treated with fumagillin. Thrombocytopenia occurred but without major adverse events. Modifications of immunosuppression could be avoided when E. bieneusi is rapidly identified and fumagillin therapy is started promptly.
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spelling doaj.art-c473637ad79148138d76c643b42cbcc92022-12-22T01:41:53ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592017-06-012361039104110.3201/eid2306.161825Enterocytozoon bieneusi Microsporidiosis in Stem Cell Transplant Recipients Treated with FumagillinIryna BukreyevaAdela AngoulvantInès BendibJean-Charles GagnardJean-Henri BourhisSylvie DargèreJulie BonhommeMarc ThellierBertrand GachotBenjamin WyploszEnterocytozoon bieneusi microsporidiosis is an emerging disease in immunocompromised patients. We report 2 cases of this disease in allogeneic hematopoietic stem cell transplant patients successfully treated with fumagillin. Thrombocytopenia occurred but without major adverse events. Modifications of immunosuppression could be avoided when E. bieneusi is rapidly identified and fumagillin therapy is started promptly.https://wwwnc.cdc.gov/eid/article/23/6/16-1825_articleEnterocytozoon bieneusiprotozoamicrosporidiamicrosporidiosisparasitesobligate intracellular parasite
spellingShingle Iryna Bukreyeva
Adela Angoulvant
Inès Bendib
Jean-Charles Gagnard
Jean-Henri Bourhis
Sylvie Dargère
Julie Bonhomme
Marc Thellier
Bertrand Gachot
Benjamin Wyplosz
Enterocytozoon bieneusi Microsporidiosis in Stem Cell Transplant Recipients Treated with Fumagillin
Emerging Infectious Diseases
Enterocytozoon bieneusi
protozoa
microsporidia
microsporidiosis
parasites
obligate intracellular parasite
title Enterocytozoon bieneusi Microsporidiosis in Stem Cell Transplant Recipients Treated with Fumagillin
title_full Enterocytozoon bieneusi Microsporidiosis in Stem Cell Transplant Recipients Treated with Fumagillin
title_fullStr Enterocytozoon bieneusi Microsporidiosis in Stem Cell Transplant Recipients Treated with Fumagillin
title_full_unstemmed Enterocytozoon bieneusi Microsporidiosis in Stem Cell Transplant Recipients Treated with Fumagillin
title_short Enterocytozoon bieneusi Microsporidiosis in Stem Cell Transplant Recipients Treated with Fumagillin
title_sort enterocytozoon bieneusi microsporidiosis in stem cell transplant recipients treated with fumagillin
topic Enterocytozoon bieneusi
protozoa
microsporidia
microsporidiosis
parasites
obligate intracellular parasite
url https://wwwnc.cdc.gov/eid/article/23/6/16-1825_article
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