Research advances in the correlations between periodontal disease and autophagy
Periodontal disease is a common and frequently occurring oral disease, with numerous investigations on periodontitis etiology and treatment. The development of periodontal disease is affected by many factors, including local stimulation and systemic risk factors, and dental plaque biofilm is regar...
| Main Authors: | , |
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| Format: | Article |
| Language: | zho |
| Published: |
Editorial Department of Journal of Prevention and Treatment for Stomatological Diseases
2018-04-01
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| Series: | 口腔疾病防治 |
| Subjects: | |
| Online Access: | http://www.kqjbfz.com/EN/10.12016/j.issn.2096-1456.2018.04.014 |
| Summary: | Periodontal disease is a common and frequently occurring oral disease, with numerous investigations on
periodontitis etiology and treatment. The development of periodontal disease is affected by many factors, including local
stimulation and systemic risk factors, and dental plaque biofilm is regarded as an initial factor. The molecular mecha⁃
nisms of how dental plaque biofilm and other risk factors regulate the development of periodontal disease remain un⁃
clear. Autophagy is a ubiquitous self⁃regulating mechanism of eukaryotes and a process of cell self⁃phagocytosis and di⁃
gestion. Autophagy is a complex process, involving a variety of cellular and tissue activities, including cellular stress,
clearance of endogenous and exogenous cellular components, development, aging and cancer. Recent studies have
shown that autophagy is closely related to inflammation. This paper addresses recent research advances in understand⁃
ing the correlations between periodontal disease and autophagy to provide a reference in the study of new methods to
treat periodontal disease from the perspective of autophagy in the future. |
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| ISSN: | 2096-1456 2096-1456 |