Research advances in the correlations between periodontal disease and autophagy

Periodontal disease is a common and frequently occurring oral disease, with numerous investigations on periodontitis etiology and treatment. The development of periodontal disease is affected by many factors, including local stimulation and systemic risk factors, and dental plaque biofilm is regar...

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Main Authors: LIU Yang, ZHAO Yueping
Format: Article
Language:zho
Published: Editorial Department of Journal of Prevention and Treatment for Stomatological Diseases 2018-04-01
Series:口腔疾病防治
Subjects:
Online Access:http://www.kqjbfz.com/EN/10.12016/j.issn.2096-1456.2018.04.014
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author LIU Yang
ZHAO Yueping
author_facet LIU Yang
ZHAO Yueping
author_sort LIU Yang
collection DOAJ
description Periodontal disease is a common and frequently occurring oral disease, with numerous investigations on periodontitis etiology and treatment. The development of periodontal disease is affected by many factors, including local stimulation and systemic risk factors, and dental plaque biofilm is regarded as an initial factor. The molecular mecha⁃ nisms of how dental plaque biofilm and other risk factors regulate the development of periodontal disease remain un⁃ clear. Autophagy is a ubiquitous self⁃regulating mechanism of eukaryotes and a process of cell self⁃phagocytosis and di⁃ gestion. Autophagy is a complex process, involving a variety of cellular and tissue activities, including cellular stress, clearance of endogenous and exogenous cellular components, development, aging and cancer. Recent studies have shown that autophagy is closely related to inflammation. This paper addresses recent research advances in understand⁃ ing the correlations between periodontal disease and autophagy to provide a reference in the study of new methods to treat periodontal disease from the perspective of autophagy in the future.
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spelling doaj.art-c476e31ea1544c44bb05c5dbd27cddf02022-12-22T00:52:19ZzhoEditorial Department of Journal of Prevention and Treatment for Stomatological Diseases口腔疾病防治2096-14562096-14562018-04-0126426827210.12016/j.issn.2096-1456.2018.04.014Research advances in the correlations between periodontal disease and autophagyLIU Yang0ZHAO Yueping1 Stomatology College of Jinan University Stomatology College of Jinan UniversityPeriodontal disease is a common and frequently occurring oral disease, with numerous investigations on periodontitis etiology and treatment. The development of periodontal disease is affected by many factors, including local stimulation and systemic risk factors, and dental plaque biofilm is regarded as an initial factor. The molecular mecha⁃ nisms of how dental plaque biofilm and other risk factors regulate the development of periodontal disease remain un⁃ clear. Autophagy is a ubiquitous self⁃regulating mechanism of eukaryotes and a process of cell self⁃phagocytosis and di⁃ gestion. Autophagy is a complex process, involving a variety of cellular and tissue activities, including cellular stress, clearance of endogenous and exogenous cellular components, development, aging and cancer. Recent studies have shown that autophagy is closely related to inflammation. This paper addresses recent research advances in understand⁃ ing the correlations between periodontal disease and autophagy to provide a reference in the study of new methods to treat periodontal disease from the perspective of autophagy in the future.http://www.kqjbfz.com/EN/10.12016/j.issn.2096-1456.2018.04.014Periodontal diseaseEtiologyCellAutophagyDental plaque biofilmTobacco smokingTreatment
spellingShingle LIU Yang
ZHAO Yueping
Research advances in the correlations between periodontal disease and autophagy
口腔疾病防治
Periodontal disease
Etiology
Cell
Autophagy
Dental plaque biofilm
Tobacco smoking
Treatment
title Research advances in the correlations between periodontal disease and autophagy
title_full Research advances in the correlations between periodontal disease and autophagy
title_fullStr Research advances in the correlations between periodontal disease and autophagy
title_full_unstemmed Research advances in the correlations between periodontal disease and autophagy
title_short Research advances in the correlations between periodontal disease and autophagy
title_sort research advances in the correlations between periodontal disease and autophagy
topic Periodontal disease
Etiology
Cell
Autophagy
Dental plaque biofilm
Tobacco smoking
Treatment
url http://www.kqjbfz.com/EN/10.12016/j.issn.2096-1456.2018.04.014
work_keys_str_mv AT liuyang researchadvancesinthecorrelationsbetweenperiodontaldiseaseandautophagy
AT zhaoyueping researchadvancesinthecorrelationsbetweenperiodontaldiseaseandautophagy