Evidence of White Matter Integrity Changes in the Anterior Cingulum Among Shift Workers: A Cross-Sectional Study
Jiye Lee,1,* Minjeong Kim,1,* Nambeom Kim,2 Yunjee Hwang,1 Kyung Hwa Lee,3,4 Jooyoung Lee,1 Yu Jin Lee,3 Seog Ju Kim1 1Department of Psychiatry, Sungkyunkwan University College of Medicine, Samsung Medical Center, Seoul, Republic of Korea; 2Department of Biomedical Engineering Resear...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Dove Medical Press
2022-08-01
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| Series: | Nature and Science of Sleep |
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| Online Access: | https://www.dovepress.com/evidence-of-white-matter-integrity-changes-in-the-anterior-cingulum-am-peer-reviewed-fulltext-article-NSS |
| _version_ | 1798041889506590720 |
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| author | Lee J Kim M Kim N Hwang Y Lee KH Lee J Lee YJ Kim SJ |
| author_facet | Lee J Kim M Kim N Hwang Y Lee KH Lee J Lee YJ Kim SJ |
| author_sort | Lee J |
| collection | DOAJ |
| description | Jiye Lee,1,* Minjeong Kim,1,* Nambeom Kim,2 Yunjee Hwang,1 Kyung Hwa Lee,3,4 Jooyoung Lee,1 Yu Jin Lee,3 Seog Ju Kim1 1Department of Psychiatry, Sungkyunkwan University College of Medicine, Samsung Medical Center, Seoul, Republic of Korea; 2Department of Biomedical Engineering Research Center, Gachon University, Incheon, Republic of Korea; 3Department of Psychiatry and Center for Sleep and Chronobiology, Seoul National University, College of Medicine and Hospital, Seoul, Republic of Korea; 4Division of Child and Adolescent Psychiatry, Department of Psychiatry, Seoul National University Hospital, Seoul, Republic of Korea*These authors contributed equally to this workCorrespondence: Yu Jin Lee, Department of Psychiatry and Center for Sleep and Chronobiology, Seoul National University, College of Medicine and Hospital, Seoul, Republic of Korea, Email ewpsyche@snu.ac.kr Seog Ju Kim, Department of Psychiatry, Sungkyunkwan University College of Medicine, Samsung Medical Center, Seoul, Republic of Korea, Email ksj7126@skku.eduIntroduction: We investigated the white matter integrity in shift and non-shift workers and its associations with sleep and activity.Methods: Diffusion tensor imaging (DTI) was performed on 61 shift workers and 31 non-shift workers. Their sleep and activity profiles were assessed using the Pittsburgh Sleep Quality Index (PSQI), sleep diaries, and actigraphy. Fractional anisotropy (FA) (a measure of white matter integrity) was calculated using DTI tractography.Results: Shift workers exhibited higher FA values in the bilateral anterior cingulum than did non-shift workers. An increased FA in the right anterior cingulum was correlated with poor sleep quality (ie, a high PSQI score) in shift workers. An increased FA in the right anterior cingulum was also correlated with higher actigraphic activity indices (the mesor and M10 indices) in shift workers.Discussion: The white matter integrity of the anterior cingulum was altered in shift workers, perhaps in association with sleep and activity disturbances.Keywords: shift work, DTI, cingulum, sleep, activity |
| first_indexed | 2024-04-11T22:27:51Z |
| format | Article |
| id | doaj.art-c47bb550cd994b39952e6515ce967afe |
| institution | Directory Open Access Journal |
| issn | 1179-1608 |
| language | English |
| last_indexed | 2024-04-11T22:27:51Z |
| publishDate | 2022-08-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | Nature and Science of Sleep |
| spelling | doaj.art-c47bb550cd994b39952e6515ce967afe2022-12-22T03:59:36ZengDove Medical PressNature and Science of Sleep1179-16082022-08-01Volume 141417142577420Evidence of White Matter Integrity Changes in the Anterior Cingulum Among Shift Workers: A Cross-Sectional StudyLee JKim MKim NHwang YLee KHLee JLee YJKim SJJiye Lee,1,* Minjeong Kim,1,* Nambeom Kim,2 Yunjee Hwang,1 Kyung Hwa Lee,3,4 Jooyoung Lee,1 Yu Jin Lee,3 Seog Ju Kim1 1Department of Psychiatry, Sungkyunkwan University College of Medicine, Samsung Medical Center, Seoul, Republic of Korea; 2Department of Biomedical Engineering Research Center, Gachon University, Incheon, Republic of Korea; 3Department of Psychiatry and Center for Sleep and Chronobiology, Seoul National University, College of Medicine and Hospital, Seoul, Republic of Korea; 4Division of Child and Adolescent Psychiatry, Department of Psychiatry, Seoul National University Hospital, Seoul, Republic of Korea*These authors contributed equally to this workCorrespondence: Yu Jin Lee, Department of Psychiatry and Center for Sleep and Chronobiology, Seoul National University, College of Medicine and Hospital, Seoul, Republic of Korea, Email ewpsyche@snu.ac.kr Seog Ju Kim, Department of Psychiatry, Sungkyunkwan University College of Medicine, Samsung Medical Center, Seoul, Republic of Korea, Email ksj7126@skku.eduIntroduction: We investigated the white matter integrity in shift and non-shift workers and its associations with sleep and activity.Methods: Diffusion tensor imaging (DTI) was performed on 61 shift workers and 31 non-shift workers. Their sleep and activity profiles were assessed using the Pittsburgh Sleep Quality Index (PSQI), sleep diaries, and actigraphy. Fractional anisotropy (FA) (a measure of white matter integrity) was calculated using DTI tractography.Results: Shift workers exhibited higher FA values in the bilateral anterior cingulum than did non-shift workers. An increased FA in the right anterior cingulum was correlated with poor sleep quality (ie, a high PSQI score) in shift workers. An increased FA in the right anterior cingulum was also correlated with higher actigraphic activity indices (the mesor and M10 indices) in shift workers.Discussion: The white matter integrity of the anterior cingulum was altered in shift workers, perhaps in association with sleep and activity disturbances.Keywords: shift work, DTI, cingulum, sleep, activityhttps://www.dovepress.com/evidence-of-white-matter-integrity-changes-in-the-anterior-cingulum-am-peer-reviewed-fulltext-article-NSSshift workdticingulumsleepactivity |
| spellingShingle | Lee J Kim M Kim N Hwang Y Lee KH Lee J Lee YJ Kim SJ Evidence of White Matter Integrity Changes in the Anterior Cingulum Among Shift Workers: A Cross-Sectional Study Nature and Science of Sleep shift work dti cingulum sleep activity |
| title | Evidence of White Matter Integrity Changes in the Anterior Cingulum Among Shift Workers: A Cross-Sectional Study |
| title_full | Evidence of White Matter Integrity Changes in the Anterior Cingulum Among Shift Workers: A Cross-Sectional Study |
| title_fullStr | Evidence of White Matter Integrity Changes in the Anterior Cingulum Among Shift Workers: A Cross-Sectional Study |
| title_full_unstemmed | Evidence of White Matter Integrity Changes in the Anterior Cingulum Among Shift Workers: A Cross-Sectional Study |
| title_short | Evidence of White Matter Integrity Changes in the Anterior Cingulum Among Shift Workers: A Cross-Sectional Study |
| title_sort | evidence of white matter integrity changes in the anterior cingulum among shift workers a cross sectional study |
| topic | shift work dti cingulum sleep activity |
| url | https://www.dovepress.com/evidence-of-white-matter-integrity-changes-in-the-anterior-cingulum-am-peer-reviewed-fulltext-article-NSS |
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