Insulin Resistance as a Shared Pathogenic Mechanism Between Depression and Type 2 Diabetes

Insulin Resistance as a Shared Pathogenic Mechanism Between Depression and Type 2 Diabetes

Neuropsychiatric disorders and type 2 diabetes (T2D) are major public health concerns proposed to be intimately connected. T2D is associated with increased risk of dementia, neuropsychiatric and mood disorders. Evidences of the involvement of insulin signaling on brain mechanisms related to depressi...

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Bibliographic Details
Main Authors: Natalia de M. Lyra e Silva, Minh P. Lam, Claudio N. Soares, Douglas P. Munoz, Roumen Milev, Fernanda G. De Felice
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Psychiatry
Subjects:
depression
type 2 diabetes
insulin resistance
inflammation
synaptic plasticity
hippocampus
Online Access:https://www.frontiersin.org/article/10.3389/fpsyt.2019.00057/full

Internet

https://www.frontiersin.org/article/10.3389/fpsyt.2019.00057/full

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