Characterization of α-Glucosidase Inhibitors from Clinacanthus nutans Lindau Leaves by Gas Chromatography-Mass Spectrometry-Based Metabolomics and Molecular Docking Simulation

Characterization of α-Glucosidase Inhibitors from Clinacanthus nutans Lindau Leaves by Gas Chromatography-Mass Spectrometry-Based Metabolomics and Molecular Docking Simulation

Background: Clinacanthus nutans (C. nutans) is an Acanthaceae herbal shrub traditionally consumed to treat various diseases including diabetes in Malaysia. This study was designed to evaluate the α-glucosidase inhibitory activity of C. nutans leaves extracts, and to identify the metabolite...

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Bibliographic Details
Main Authors: Suganya Murugesu, Zalikha Ibrahim, Qamar-Uddin Ahmed, Nik-Idris Nik Yusoff, Bisha-Fathamah Uzir, Vikneswari Perumal, Faridah Abas, Khozirah Saari, Hesham El-Seedi, Alfi Khatib
Format: Article
Language:English
Published: MDPI AG 2018-09-01
Series:Molecules
Subjects:
α-glucosidase inhibitors
Clinacanthus nutans
diabetes
GC-MS
partial least square
Online Access:http://www.mdpi.com/1420-3049/23/9/2402

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