The prevalence of gastroesophageal reflux disease and reflux esophagitis in dialysis patients: between facts and fiction
The prevalence of gastroesophageal reflux disease (GERD) in end-stage renal disease (ESRD) patients who are on regular hemodialysis (HD) and those who are on peritoneal dialysis (PD) has been a subject of discussion over the past decades. Although, to our knowledge, few studies have compared the pre...
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| Format: | Article |
| Language: | English |
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PAGEPress Publications
2013-04-01
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| Series: | Italian Journal of Medicine |
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| Online Access: | http://www.italjmed.org/index.php/ijm/article/view/165 |
| _version_ | 1797423654444728320 |
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| author | Ibrahiem Saeed Abdul-Rahman |
| author_facet | Ibrahiem Saeed Abdul-Rahman |
| author_sort | Ibrahiem Saeed Abdul-Rahman |
| collection | DOAJ |
| description | The prevalence of gastroesophageal reflux disease (GERD) in end-stage renal disease (ESRD) patients who are on regular hemodialysis (HD) and those who are on peritoneal dialysis (PD) has been a subject of discussion over the past decades. Although, to our knowledge, few studies have compared the prevalence of GERD in both groups of patients, yet most authorities believe that the disease is more prevalent in PD patients. The aim of the current study is to clarify the relation between dialysis modalities and GERD. The study involved 68 ESRD patients who are on regular hemodialysis (group 1) and 71 age- and sex-matched ESRD patients on peritoneal dialysis (group 2). All patients were subjected to esophago-gastroduodenoscopy for proper evaluation. The prevalence of GERD and reflux esophagitis (RE) was similar in the two groups (45.6% <em>vs</em> 47.9.2% and 36.8% <em>vs</em> 39.4% respectively) (P>0.05). The duration of dialysis, serum creatinine of 7 or over, the presence of diabetes mellitus, body mass index of 27 kg/m<sup>2</sup> or over, smoking and the absence of <em>H. pylori </em>infection were significantly associated with GERD and RE, while the dialysis modality, age, gender, use of nonsteroidal anti-inflammatory drugs, hypoalbuminemia and aspirin use were not. This study shows a similar prevalence of GERD and RE in both HD and PD patients. The duration rather than the modality of dialysis correlated significantly with GERD and RE. |
| first_indexed | 2024-03-09T07:51:04Z |
| format | Article |
| id | doaj.art-c481feab9577496d8585036182a6511c |
| institution | Directory Open Access Journal |
| issn | 1877-9344 1877-9352 |
| language | English |
| last_indexed | 2024-03-09T07:51:04Z |
| publishDate | 2013-04-01 |
| publisher | PAGEPress Publications |
| record_format | Article |
| series | Italian Journal of Medicine |
| spelling | doaj.art-c481feab9577496d8585036182a6511c2023-12-03T02:02:52ZengPAGEPress PublicationsItalian Journal of Medicine1877-93441877-93522013-04-017211812310.4081/itjm.2013.118135The prevalence of gastroesophageal reflux disease and reflux esophagitis in dialysis patients: between facts and fictionIbrahiem Saeed Abdul-Rahman0Department of Internal Medicine, Nephrology Division, King Fahd University Hospital, Dammam UniversityThe prevalence of gastroesophageal reflux disease (GERD) in end-stage renal disease (ESRD) patients who are on regular hemodialysis (HD) and those who are on peritoneal dialysis (PD) has been a subject of discussion over the past decades. Although, to our knowledge, few studies have compared the prevalence of GERD in both groups of patients, yet most authorities believe that the disease is more prevalent in PD patients. The aim of the current study is to clarify the relation between dialysis modalities and GERD. The study involved 68 ESRD patients who are on regular hemodialysis (group 1) and 71 age- and sex-matched ESRD patients on peritoneal dialysis (group 2). All patients were subjected to esophago-gastroduodenoscopy for proper evaluation. The prevalence of GERD and reflux esophagitis (RE) was similar in the two groups (45.6% <em>vs</em> 47.9.2% and 36.8% <em>vs</em> 39.4% respectively) (P>0.05). The duration of dialysis, serum creatinine of 7 or over, the presence of diabetes mellitus, body mass index of 27 kg/m<sup>2</sup> or over, smoking and the absence of <em>H. pylori </em>infection were significantly associated with GERD and RE, while the dialysis modality, age, gender, use of nonsteroidal anti-inflammatory drugs, hypoalbuminemia and aspirin use were not. This study shows a similar prevalence of GERD and RE in both HD and PD patients. The duration rather than the modality of dialysis correlated significantly with GERD and RE.http://www.italjmed.org/index.php/ijm/article/view/165gastroesophageal reflux disease, esophagitis, hemodialysis, peritoneal dialysis, diabetes mellitus, body mass index, H. pylori. |
| spellingShingle | Ibrahiem Saeed Abdul-Rahman The prevalence of gastroesophageal reflux disease and reflux esophagitis in dialysis patients: between facts and fiction Italian Journal of Medicine gastroesophageal reflux disease, esophagitis, hemodialysis, peritoneal dialysis, diabetes mellitus, body mass index, H. pylori. |
| title | The prevalence of gastroesophageal reflux disease and reflux esophagitis in dialysis patients: between facts and fiction |
| title_full | The prevalence of gastroesophageal reflux disease and reflux esophagitis in dialysis patients: between facts and fiction |
| title_fullStr | The prevalence of gastroesophageal reflux disease and reflux esophagitis in dialysis patients: between facts and fiction |
| title_full_unstemmed | The prevalence of gastroesophageal reflux disease and reflux esophagitis in dialysis patients: between facts and fiction |
| title_short | The prevalence of gastroesophageal reflux disease and reflux esophagitis in dialysis patients: between facts and fiction |
| title_sort | prevalence of gastroesophageal reflux disease and reflux esophagitis in dialysis patients between facts and fiction |
| topic | gastroesophageal reflux disease, esophagitis, hemodialysis, peritoneal dialysis, diabetes mellitus, body mass index, H. pylori. |
| url | http://www.italjmed.org/index.php/ijm/article/view/165 |
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