Novel ovarian endometriosis model causes infertility via iron-mediated oxidative stress in mice

Novel ovarian endometriosis model causes infertility via iron-mediated oxidative stress in mice

Ovarian endometriosis (OE) provides women of reproductive age with not only severe menstrual pain but also infertility and an increased risk for ovarian carcinogenesis. Whereas peritoneal endometriosis models have been developed with syngeneic implantation of minced uterine tissue and oncogenic K-ra...

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Bibliographic Details
Main Authors: Shotaro Hayashi, Tomoko Nakamura, Yashiro Motooka, Fumiya Ito, Li Jiang, Shinya Akatsuka, Akira Iwase, Hiroaki Kajiyama, Fumitaka Kikkawa, Shinya Toyokuni
Format: Article
Language:English
Published: Elsevier 2020-10-01
Series:Redox Biology
Subjects:
Ovarian endometriosis
Mouse model
Iron
Oxidative stress
Follicle stimulating hormone receptor
Infertility
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231720309319

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