FKBP12-Dependent Inhibition of Calcineurin Mediates Immunosuppressive Antifungal Drug Action in <italic toggle="yes">Malassezia</italic>

FKBP12-Dependent Inhibition of Calcineurin Mediates Immunosuppressive Antifungal Drug Action in <italic toggle="yes">Malassezia</italic>

ABSTRACT The genus Malassezia includes yeasts that are commonly found on the skin or hair of animals and humans as commensals and are associated with a number of skin disorders. We have previously developed an Agrobacterium tumefaciens transformation system effective for both targeted gene deletion...

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Bibliographic Details
Main Authors: Giuseppe Ianiri, Shelly Applen Clancey, Soo Chan Lee, Joseph Heitman
Format: Article
Language:English
Published: American Society for Microbiology 2017-11-01
Series:mBio
Subjects:
FKBP12-binding protein
Malassezia
calcineurin inhibitors
hypermutator
Online Access:https://journals.asm.org/doi/10.1128/mBio.01752-17

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