Cytochrome P-450 CYP2C19 genetic polymorphism and its relation with clopidogrel resistance

Cytochrome P-450 CYP2C19 genetic polymorphism and its relation with clopidogrel resistance

Objectives: To find out the prevalence of CYP2C19*2 genetic polymorphism in ischemic heart disease patients, and to determine its relation with clopidogrel resistance in different genotype groups. Method: The cross-sectional study was conducted from August 2015 to December 2019 at the Army Medica...

Full description

Bibliographic Details
Main Authors:	Usman Nawaz, Mudassar Noor, Akbar Waheed
Format:	Article
Language:	English
Published:	Pakistan Medical Association 2023-11-01
Series:	Journal of the Pakistan Medical Association
Subjects:	CYP2C19 Genetic polymorphism Clopidogrel
Online Access:	https://www.ojs.jpma.org.pk/index.php/public_html/article/view/8025

Similar Items

The polymorphism of cytochrome P450 CYP2C19 and resistance to clopidogrel.
by: C. Simoglou
Published: (2017-03-01)

CYP 450 2C19 polymorphisms in Indian patients with coronary artery disease
by: Sudhir S. Shetkar, et al.
Published: (2014-01-01)

The correlation between CYP2C19 Polymorphisms and recurrent risk in Patients with Ischemic Stroke treated with Clopidogrel in Kurdistan region-Iraq
by: Hind Salim Jardaq, et al.
Published: (2022-12-01)

CLOPIDOGREL RESPONSE IN ACUTE CORONARY SYNDROME PATIENTS WITH CYP2Y12*2 AND CYP2Y12*3 POLYMORPHISMS
by: R. Rahmatini, et al.
Published: (2018-04-01)

CYP2C19 genetic variation and individualized clopidogrel prescription in a cardiology clinic
by: Seyed abbas Mirabbasi, et al.
Published: (2017-07-01)

Genetic Polymorphisms of CYP2C19 and Resistance to Clopidogrel Therapy among Iranian Patients Suffering from Ischemic Heart Disease
by: Behzad Poopak, et al.
Published: (2016-07-01)

Effects of Triflusal and Clopidogrel on the Secondary Prevention of Stroke Based on Cytochrome P450 2C19 Genotyping
by: Sang Won Han, et al.
Published: (2017-09-01)

ACC/AHA CLOPIDOGREL CLINICAL ALERT. WHAT MUST BE MODERN ANTIPLATELET THERAPY?
by: S. J. Martsevich
Published: (2016-01-01)

Influence of CYP450 Enzymes and ABCB1 Polymorphisms on Clopidogrel Response in Moroccan Patients with Acute Coronary Syndromes
by: Mouhrach I, et al.
Published: (2023-10-01)

CYP2C19*1 and CYP2C19*2 Polymorphism in Turkish Patients Being Diagnosed with Stable Coronary Artery Disease and Using Clopidogrel
by: Ramazan Sabırlı, et al.
Published: (2021-03-01)

CYP2C19 polymorphisms and lipoproteins associated with clopidogrel resistance in children with Kawasaki disease in China: A prospective study
by: Mingming Zhang, et al.
Published: (2022-08-01)

CYP2C19 Genetic Polymorphism in the East of Iran: Its Association with the Severity and Pattern of Coronary Artery Disease
by: Mahdi Zahedi, et al.
Published: (2019-03-01)

Polymorphisms of MDR1, CYP2C19 and P2Y12 genes in Indian population: Effects on clopidogrel response
by: Kavita K. Shalia, et al.
Published: (2013-03-01)

Impacts of CYP2C19 Polymorphism and Clopidogrel Dosing on in-Stent Restenosis: A Retrospective Cohort Study in Chinese Patients
by: Zhang M, et al.
Published: (2020-02-01)

The Role of Genetic Polymorphism and Other Factors on Clopidogrel Resistance (CR) in an Asian Population with Coronary Heart Disease (CHD)
by: Mohammed Ahmed Akkaif, et al.
Published: (2021-04-01)

Cyp2C19*2 Polymorphism Related to Clopidogrel Resistance in Patients With Coronary Heart Disease, Especially in the Asian Population: A Systematic Review and Meta-Analysis
by: Ying Sun, et al.
Published: (2020-12-01)

CYP2C19 Polymorphism in Ischemic Heart Disease Patients Taking Clopidogrel After Percutaneous Coronary Intervention in Egypt
by: Ahmed Shawky, et al.
Published: (2023-05-01)

Prevalence of CYP2C19*2 and CYP2C19*3 Allelic Variants and Clopidogrel Use in Patients with Cardiovascular Disease in Trinidad & Tobago
by: Daniele Jones, et al.
Published: (2024-01-01)

Pharmacogenomic Impact of CYP2C19 Variation on Clopidogrel Therapy in Precision Cardiovascular Medicine
by: Sherry-Ann Brown, et al.
Published: (2018-01-01)

Genetic polymorphism of clopidogrel metabolism related gene CYP2C19 gene in Chinese from Foshan area of Guangdong Province
by: Xiao-wen Yuan, et al.
Published: (2022-12-01)

The association between CYP2C19 genetic polymorphism and prognosis in patients receiving endovascular therapy
by: Wei Li, et al.
Published: (2024-01-01)

CYP2C19 genotype and adverse cardiovascular outcomes after stent implantation in clopidogrel-treated Asian populations: A systematic review and meta-analysis
by: Ziwei Xi, et al.
Published: (2019-02-01)

Cytochrome P450c17alpha (CYP17) gene polymorphism is not associated with leiomyoma susceptibility
by: Hsieh Yao-Yuan, et al.
Published: (2002-01-01)

Influence of CYP2C19*2 gene variant on therapeutic response during clopidogrel treatment in patients with carotid artery stenosis
by: Bačković Dragana, et al.
Published: (2016-01-01)

Effects of Cyp2c19 and P2y12 Gene Polymorphisms on Clinical Results of Patients Using Clopidogrel After Acute Ischemic Cerebrovascular Disease
by: Sen H. M., et al.
Published: (2014-12-01)

CYP2C19 gene polymorphism and its impact on the long-term prognosis after myocardial infarction
by: Mariya V. Solodun, et al.
Published: (2022-07-01)

Substantiation of a clopidogrel metabolism-associated gene (CYP2C19) variation among healthy individuals
by: Anshu Kumar Yadav, et al.
Published: (2023-09-01)

Analysis of CYP2C19 gene polymorphism and influencing factors of pharmacological response of clopidogrel in patients with cerebral infarction in Zhejiang, China
by: Yijun Mo, et al.
Published: (2023-02-01)

Investigation of cytochrome p450 CYP1A2, CYP2D6, CYP2E1 and CYP3A4 gene expressions and polymorphisms in alcohol withdrawal (eng)
by: Nazife Taşçıoğlu, et al.
Published: (2021-09-01)

The diversity and clinical implications of genetic variants influencing clopidogrel bioactivation and response in the Emirati population
by: Lubna Q. Khasawneh, et al.
Published: (2024-01-01)

Impact of CYP2C19 variants on clinical efficacy of clopidogrel and one-year clinical outcomes in coronary heart patients undergoing percutaneous coronary intervention
by: Hong Sun, et al.
Published: (2016-11-01)

Role of genetic factors on the effect of additional loading doses and two maintenance doses used to overcome clopidogrel hyporesponsiveness
by: Gustavs Latkovskis, et al.
Published: (2014-01-01)

Effect of genetic polymorphisms on the interplay of P-glycoprotein transporter and cytochrome P450 enzymes: Pharmacokinetics of risperidone
by: Yong-Bok Lee
Published: (2016-02-01)

Gene polymorphism of cytochrome P450 significantly affects lung cancer susceptibility
by: Meng Li, et al.
Published: (2019-08-01)

Genetic Polymorphism of Cytochrome p450 (2C19) Enzyme in Iranian Turkman Ethnic Group
by: Robabeh Ghiyas Tabari, et al.
Published: (2013-07-01)

CLOPIDOGREL PHARMACOGENETICS
by: A. N. Meshkov
Published: (2016-01-01)

miR-6076 rs1463411 polymorphisms are associated with bleeding during clopidogrel treatment in patients with acute coronary syndrome
by: Zhen-Zhen Mo, et al.
Published: (2023-02-01)

Serotonin syndrome caused by a CYP2C19-mediated interaction between low-dose escitalopram and clopidogrel: a case report
by: Jianhong Wu, et al.
Published: (2023-10-01)

Effect of original and generic clopidogrel on prognosis in relation to different gene polymorphisms
by: D F Mesitskaia, et al.
Published: (2014-09-01)

The impact of cytochrome 450 and Paraoxonase polymorphisms on clopidogrel resistance and major adverse cardiac events in coronary heart disease patients after percutaneous coronary intervention
by: Zhaowei Zhang, et al.
Published: (2020-01-01)