Zinc Oxide Nanoparticles Induce DNA Damage in Sand Dollar <i>Scaphechinus mirabilis</i> Sperm
Products containing nanomaterials are becoming more and more common in everyday life. Zinc oxide nanoparticles (ZnO NPs), meanwhile, are among the most widely used NPs. However, their genotoxic effect on the germ products of marine organisms is poorly understood. Therefore, the effects of ZnO NPs an...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-06-01
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| Series: | Toxics |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2305-6304/10/7/348 |
| _version_ | 1827603843850960896 |
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| author | Sergey Petrovich Kukla Victor Pavlovich Chelomin Andrey Alexandrovich Mazur Valentina Vladimirovna Slobodskova |
| author_facet | Sergey Petrovich Kukla Victor Pavlovich Chelomin Andrey Alexandrovich Mazur Valentina Vladimirovna Slobodskova |
| author_sort | Sergey Petrovich Kukla |
| collection | DOAJ |
| description | Products containing nanomaterials are becoming more and more common in everyday life. Zinc oxide nanoparticles (ZnO NPs), meanwhile, are among the most widely used NPs. However, their genotoxic effect on the germ products of marine organisms is poorly understood. Therefore, the effects of ZnO NPs and zinc ions (20, 50, 100, 200 µg/L) on the sperm of sand dollar <i>Scaphechinus mirabilis</i> were compared. Comet assay showed that both tested pollutants caused an increase in DNA damage to 6.57 ± 2.41 and 7.42 ± 0.88% DNA in the comet tail, for zinc ions and ZnO NPs, respectively. Additionally, a different pattern was shown by the increase in DNA damage, with increasing concentration of pollutants, in different experimental groups. |
| first_indexed | 2024-03-09T05:47:29Z |
| format | Article |
| id | doaj.art-c48c47dc0c574993a903cb29b36f36be |
| institution | Directory Open Access Journal |
| issn | 2305-6304 |
| language | English |
| last_indexed | 2024-03-09T05:47:29Z |
| publishDate | 2022-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Toxics |
| spelling | doaj.art-c48c47dc0c574993a903cb29b36f36be2023-12-03T12:20:28ZengMDPI AGToxics2305-63042022-06-0110734810.3390/toxics10070348Zinc Oxide Nanoparticles Induce DNA Damage in Sand Dollar <i>Scaphechinus mirabilis</i> SpermSergey Petrovich Kukla0Victor Pavlovich Chelomin1Andrey Alexandrovich Mazur2Valentina Vladimirovna Slobodskova3Il’ichev Pacific Oceanological Institute, Far Eastern Branch, Russian Academy of Sciences, 690041 Vladivostok, RussiaIl’ichev Pacific Oceanological Institute, Far Eastern Branch, Russian Academy of Sciences, 690041 Vladivostok, RussiaIl’ichev Pacific Oceanological Institute, Far Eastern Branch, Russian Academy of Sciences, 690041 Vladivostok, RussiaIl’ichev Pacific Oceanological Institute, Far Eastern Branch, Russian Academy of Sciences, 690041 Vladivostok, RussiaProducts containing nanomaterials are becoming more and more common in everyday life. Zinc oxide nanoparticles (ZnO NPs), meanwhile, are among the most widely used NPs. However, their genotoxic effect on the germ products of marine organisms is poorly understood. Therefore, the effects of ZnO NPs and zinc ions (20, 50, 100, 200 µg/L) on the sperm of sand dollar <i>Scaphechinus mirabilis</i> were compared. Comet assay showed that both tested pollutants caused an increase in DNA damage to 6.57 ± 2.41 and 7.42 ± 0.88% DNA in the comet tail, for zinc ions and ZnO NPs, respectively. Additionally, a different pattern was shown by the increase in DNA damage, with increasing concentration of pollutants, in different experimental groups.https://www.mdpi.com/2305-6304/10/7/348ZnO NPsgenotoxicity<i>Scaphechinus mirabilis</i>comet assay |
| spellingShingle | Sergey Petrovich Kukla Victor Pavlovich Chelomin Andrey Alexandrovich Mazur Valentina Vladimirovna Slobodskova Zinc Oxide Nanoparticles Induce DNA Damage in Sand Dollar <i>Scaphechinus mirabilis</i> Sperm Toxics ZnO NPs genotoxicity <i>Scaphechinus mirabilis</i> comet assay |
| title | Zinc Oxide Nanoparticles Induce DNA Damage in Sand Dollar <i>Scaphechinus mirabilis</i> Sperm |
| title_full | Zinc Oxide Nanoparticles Induce DNA Damage in Sand Dollar <i>Scaphechinus mirabilis</i> Sperm |
| title_fullStr | Zinc Oxide Nanoparticles Induce DNA Damage in Sand Dollar <i>Scaphechinus mirabilis</i> Sperm |
| title_full_unstemmed | Zinc Oxide Nanoparticles Induce DNA Damage in Sand Dollar <i>Scaphechinus mirabilis</i> Sperm |
| title_short | Zinc Oxide Nanoparticles Induce DNA Damage in Sand Dollar <i>Scaphechinus mirabilis</i> Sperm |
| title_sort | zinc oxide nanoparticles induce dna damage in sand dollar i scaphechinus mirabilis i sperm |
| topic | ZnO NPs genotoxicity <i>Scaphechinus mirabilis</i> comet assay |
| url | https://www.mdpi.com/2305-6304/10/7/348 |
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