A Modular and Cost-Effective Droplet Microfluidic Device for Controlled Emulsion Production
The droplet microfluidic device has become a widely used tool in fields such as physics, chemistry, and biology, but its complexity has limited its widespread application. This report introduces a modular and cost-effective droplet microfluidic device for the controlled production of complex emulsio...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2024-03-01
|
| Series: | Polymers |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2073-4360/16/6/765 |
| _version_ | 1797239600520888320 |
|---|---|
| author | Hao Jiang Zhaoyue Liu Fengwei Tang Yimin Cheng Wei Tian Woda Shi Jia Ming Zhang Yajun Zhang |
| author_facet | Hao Jiang Zhaoyue Liu Fengwei Tang Yimin Cheng Wei Tian Woda Shi Jia Ming Zhang Yajun Zhang |
| author_sort | Hao Jiang |
| collection | DOAJ |
| description | The droplet microfluidic device has become a widely used tool in fields such as physics, chemistry, and biology, but its complexity has limited its widespread application. This report introduces a modular and cost-effective droplet microfluidic device for the controlled production of complex emulsions, including oil and aqueous single emulsions, and double emulsions with varying numbers of encapsulated droplets. The droplet sizes can be precisely controlled by easily replacing flat needles and adjusting the needle position within an axially accelerated co-flow field. This modular device not only allows for easy repair and maintenance in case of device clogging or damage but can also be readily expanded to produce complex emulsions. The low-cost and user-friendly nature of the device greatly facilitates the widespread adoption and utilization of droplet microfluidics. |
| first_indexed | 2024-04-24T17:54:07Z |
| format | Article |
| id | doaj.art-c48e01e1f446401aae9a81d98a34e08a |
| institution | Directory Open Access Journal |
| issn | 2073-4360 |
| language | English |
| last_indexed | 2024-04-24T17:54:07Z |
| publishDate | 2024-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Polymers |
| spelling | doaj.art-c48e01e1f446401aae9a81d98a34e08a2024-03-27T14:01:16ZengMDPI AGPolymers2073-43602024-03-0116676510.3390/polym16060765A Modular and Cost-Effective Droplet Microfluidic Device for Controlled Emulsion ProductionHao Jiang0Zhaoyue Liu1Fengwei Tang2Yimin Cheng3Wei Tian4Woda Shi5Jia Ming Zhang6Yajun Zhang7College of Mechanical and Electrical Engineering, Nanjing University of Aeronautics and Astronautics, Nanjing 210016, ChinaCollege of Mechanical and Electrical Engineering, Nanjing University of Aeronautics and Astronautics, Nanjing 210016, ChinaCollege of Mechanical and Electrical Engineering, Nanjing University of Aeronautics and Astronautics, Nanjing 210016, ChinaCollege of Mechanical and Electrical Engineering, Nanjing University of Aeronautics and Astronautics, Nanjing 210016, ChinaCollege of Mechanical and Electrical Engineering, Nanjing University of Aeronautics and Astronautics, Nanjing 210016, ChinaDepartment of Cardiothoracic Surgery, Affiliated Hospital 6 of Nantong University, The Yancheng School of Clinical Medicine, Nanjing Medical University, Yancheng Third People’s Hospital, Yancheng 224000, ChinaCollege of Mechanical and Electrical Engineering, Nanjing University of Aeronautics and Astronautics, Nanjing 210016, ChinaDepartment of Cardiothoracic Surgery, Affiliated Hospital 6 of Nantong University, The Yancheng School of Clinical Medicine, Nanjing Medical University, Yancheng Third People’s Hospital, Yancheng 224000, ChinaThe droplet microfluidic device has become a widely used tool in fields such as physics, chemistry, and biology, but its complexity has limited its widespread application. This report introduces a modular and cost-effective droplet microfluidic device for the controlled production of complex emulsions, including oil and aqueous single emulsions, and double emulsions with varying numbers of encapsulated droplets. The droplet sizes can be precisely controlled by easily replacing flat needles and adjusting the needle position within an axially accelerated co-flow field. This modular device not only allows for easy repair and maintenance in case of device clogging or damage but can also be readily expanded to produce complex emulsions. The low-cost and user-friendly nature of the device greatly facilitates the widespread adoption and utilization of droplet microfluidics.https://www.mdpi.com/2073-4360/16/6/765dropletmodularcost-effectiveemulsionmicrofluidics |
| spellingShingle | Hao Jiang Zhaoyue Liu Fengwei Tang Yimin Cheng Wei Tian Woda Shi Jia Ming Zhang Yajun Zhang A Modular and Cost-Effective Droplet Microfluidic Device for Controlled Emulsion Production Polymers droplet modular cost-effective emulsion microfluidics |
| title | A Modular and Cost-Effective Droplet Microfluidic Device for Controlled Emulsion Production |
| title_full | A Modular and Cost-Effective Droplet Microfluidic Device for Controlled Emulsion Production |
| title_fullStr | A Modular and Cost-Effective Droplet Microfluidic Device for Controlled Emulsion Production |
| title_full_unstemmed | A Modular and Cost-Effective Droplet Microfluidic Device for Controlled Emulsion Production |
| title_short | A Modular and Cost-Effective Droplet Microfluidic Device for Controlled Emulsion Production |
| title_sort | modular and cost effective droplet microfluidic device for controlled emulsion production |
| topic | droplet modular cost-effective emulsion microfluidics |
| url | https://www.mdpi.com/2073-4360/16/6/765 |
| work_keys_str_mv | AT haojiang amodularandcosteffectivedropletmicrofluidicdeviceforcontrolledemulsionproduction AT zhaoyueliu amodularandcosteffectivedropletmicrofluidicdeviceforcontrolledemulsionproduction AT fengweitang amodularandcosteffectivedropletmicrofluidicdeviceforcontrolledemulsionproduction AT yimincheng amodularandcosteffectivedropletmicrofluidicdeviceforcontrolledemulsionproduction AT weitian amodularandcosteffectivedropletmicrofluidicdeviceforcontrolledemulsionproduction AT wodashi amodularandcosteffectivedropletmicrofluidicdeviceforcontrolledemulsionproduction AT jiamingzhang amodularandcosteffectivedropletmicrofluidicdeviceforcontrolledemulsionproduction AT yajunzhang amodularandcosteffectivedropletmicrofluidicdeviceforcontrolledemulsionproduction AT haojiang modularandcosteffectivedropletmicrofluidicdeviceforcontrolledemulsionproduction AT zhaoyueliu modularandcosteffectivedropletmicrofluidicdeviceforcontrolledemulsionproduction AT fengweitang modularandcosteffectivedropletmicrofluidicdeviceforcontrolledemulsionproduction AT yimincheng modularandcosteffectivedropletmicrofluidicdeviceforcontrolledemulsionproduction AT weitian modularandcosteffectivedropletmicrofluidicdeviceforcontrolledemulsionproduction AT wodashi modularandcosteffectivedropletmicrofluidicdeviceforcontrolledemulsionproduction AT jiamingzhang modularandcosteffectivedropletmicrofluidicdeviceforcontrolledemulsionproduction AT yajunzhang modularandcosteffectivedropletmicrofluidicdeviceforcontrolledemulsionproduction |