Subclinical Hypothyroidism among Overweight and Obese Children: An Observational Cross-sectional Study
Introduction: Subclinical Hypothyroidism (SH) is often treated by thyroxine hormone by general pediatricians considering deranged thyroid profile, attributing the derangement to be the cause of obesity. However, childhood obesity increases the risk of SH by means of adaptive mechanisms. Aim: To stu...
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| Format: | Article |
| Language: | English |
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JCDR Research and Publications Private Limited
2023-01-01
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| Series: | Journal of Clinical and Diagnostic Research |
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| Online Access: | https://www.jcdr.net/articles/PDF/17263/60524_CE[Ra1]_F[SK]_PF1(AG_KM)_PFA(AG_KM)_PN(KM).pdf |
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| author | Himanshu Verma Ruchi Mishra Smriti Rohatgi Jyoti Bagla |
| author_facet | Himanshu Verma Ruchi Mishra Smriti Rohatgi Jyoti Bagla |
| author_sort | Himanshu Verma |
| collection | DOAJ |
| description | Introduction: Subclinical Hypothyroidism (SH) is often treated by thyroxine hormone by general pediatricians considering deranged thyroid profile, attributing the derangement to be the cause of obesity. However, childhood obesity increases the risk of SH by means of adaptive mechanisms.
Aim: To study the prevalence of SH and their lipid profile derangement in overweight and obese children of Indian population.
Materials and Methods: The present study was a cross-sectional study conducted in which 60 children, between 5 to 15 years of age, presenting in Department of Paediatrics at ESI PGIMSR Basaidarapur, New Delhi, India from October 2019 to April 2021 were enrolled. The children were grouped into two with 30 in each-overweight (Body Mass Index (BMI) between 23rd to 27th adult equivalent) and obese (BMI more than 27th adult equivalent) children. They were assessed for biochemical derangement including thyroid profile and lipid profile.
Results: The mean age of the study sample was 9.3 years and male/female was 41/19. Mean BMI of the obese children was 24.24 kg/m2 and that of overweight was 20.4 kg/m2. Seven (23.33%) children in overweight group and nine (30%) in obese group were diagnosed with SH (normal T4 with high TSH level). Nine out of the total 16 children with SH also had dyslipidaemia.
Conclusion: About 23% in overweight and 30% in obese children were found to have subclinical hypothyroidism. Nine out of these 16 children with subclinical hypothyroidism also had dyslipidaemia. |
| first_indexed | 2024-04-10T18:19:30Z |
| format | Article |
| id | doaj.art-c48e27e0da204a99af1fe63008800d09 |
| institution | Directory Open Access Journal |
| issn | 2249-782X 0973-709X |
| language | English |
| last_indexed | 2024-04-10T18:19:30Z |
| publishDate | 2023-01-01 |
| publisher | JCDR Research and Publications Private Limited |
| record_format | Article |
| series | Journal of Clinical and Diagnostic Research |
| spelling | doaj.art-c48e27e0da204a99af1fe63008800d092023-02-02T07:34:24ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2023-01-01171SC07SC0910.7860/JCDR/2023/60524.17263Subclinical Hypothyroidism among Overweight and Obese Children: An Observational Cross-sectional StudyHimanshu Verma0Ruchi Mishra1Smriti Rohatgi2Jyoti Bagla3Senior Resident, Department of Paediatrics, ESIPGIMSR, Basaidarapur, New Delhi, India.Associate Professor, Department of Paediatrics, ESIPGIMSR, Basaidarapur, New Delhi, India.Assistant Professor, Department of Paediatrics, ESIPGIMSR, Basaidarapur, New Delhi, India.Professor, Department of Paediatrics, ESIPGIMSR, Basaidarapur, New Delhi, India.Introduction: Subclinical Hypothyroidism (SH) is often treated by thyroxine hormone by general pediatricians considering deranged thyroid profile, attributing the derangement to be the cause of obesity. However, childhood obesity increases the risk of SH by means of adaptive mechanisms. Aim: To study the prevalence of SH and their lipid profile derangement in overweight and obese children of Indian population. Materials and Methods: The present study was a cross-sectional study conducted in which 60 children, between 5 to 15 years of age, presenting in Department of Paediatrics at ESI PGIMSR Basaidarapur, New Delhi, India from October 2019 to April 2021 were enrolled. The children were grouped into two with 30 in each-overweight (Body Mass Index (BMI) between 23rd to 27th adult equivalent) and obese (BMI more than 27th adult equivalent) children. They were assessed for biochemical derangement including thyroid profile and lipid profile. Results: The mean age of the study sample was 9.3 years and male/female was 41/19. Mean BMI of the obese children was 24.24 kg/m2 and that of overweight was 20.4 kg/m2. Seven (23.33%) children in overweight group and nine (30%) in obese group were diagnosed with SH (normal T4 with high TSH level). Nine out of the total 16 children with SH also had dyslipidaemia. Conclusion: About 23% in overweight and 30% in obese children were found to have subclinical hypothyroidism. Nine out of these 16 children with subclinical hypothyroidism also had dyslipidaemia.https://www.jcdr.net/articles/PDF/17263/60524_CE[Ra1]_F[SK]_PF1(AG_KM)_PFA(AG_KM)_PN(KM).pdfbody mass indexdyslipidaemiathyroid stimulating hormone |
| spellingShingle | Himanshu Verma Ruchi Mishra Smriti Rohatgi Jyoti Bagla Subclinical Hypothyroidism among Overweight and Obese Children: An Observational Cross-sectional Study Journal of Clinical and Diagnostic Research body mass index dyslipidaemia thyroid stimulating hormone |
| title | Subclinical Hypothyroidism among Overweight and Obese Children: An Observational Cross-sectional Study |
| title_full | Subclinical Hypothyroidism among Overweight and Obese Children: An Observational Cross-sectional Study |
| title_fullStr | Subclinical Hypothyroidism among Overweight and Obese Children: An Observational Cross-sectional Study |
| title_full_unstemmed | Subclinical Hypothyroidism among Overweight and Obese Children: An Observational Cross-sectional Study |
| title_short | Subclinical Hypothyroidism among Overweight and Obese Children: An Observational Cross-sectional Study |
| title_sort | subclinical hypothyroidism among overweight and obese children an observational cross sectional study |
| topic | body mass index dyslipidaemia thyroid stimulating hormone |
| url | https://www.jcdr.net/articles/PDF/17263/60524_CE[Ra1]_F[SK]_PF1(AG_KM)_PFA(AG_KM)_PN(KM).pdf |
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