Gray matter network properties show distinct associations with CSF p-tau 181 levels and amyloid status in individuals without dementia

Gray matter network properties show distinct associations with CSF p-tau 181 levels and amyloid status in individuals without dementia

Gray matter networks are altered with amyloid accumulation in the earliest stage of AD, and are associated with decline throughout the AD spectrum. It remains unclear to what extent gray matter network abnormalities are associated with hyperphosphorylated-tau (p-tau). We studied the relationship of...

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Bibliographic Details
Main Authors: Lorenzini Luigi, Ingala Silvia, Wottschel Viktor, Alle Meije Wink, Henk JMM Mutsaerts, Haller Sven, Blennow Kaj, John T. O'Brien, Frisoni B. Giovanni, Chételat Gael, Payoux Pierre, Martinez-Lage Pablo, Waldman Adam, Wardlaw Joanna, Ritchie Craig, Juan Domingo Gispert, Pieter Jelle Visser, Scheltens Philip, Barkhof Frederik, Betty M. Tijms
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Aging Brain
Subjects:
Brain connectivity
Gray matter networks
Preclinical Alzheimer
Tau
Amyloid
Online Access:http://www.sciencedirect.com/science/article/pii/S2589958922000263

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