Beneficial Effects of Green Tea EGCG on Skin Wound Healing: A Comprehensive Review
Epigallocatechin gallate (EGCG) is associated with various health benefits. In this review, we searched current work about the effects of EGCG and its wound dressings on skin for wound healing. Hydrogels, nanoparticles, micro/nanofiber networks and microneedles are the major types of EGCG-containing...
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| Format: | Article |
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MDPI AG
2021-10-01
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| Series: | Molecules |
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| Online Access: | https://www.mdpi.com/1420-3049/26/20/6123 |
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| author | Fa-Wei Xu Ying-Li Lv Yu-Fan Zhong Ya-Nan Xue Yong Wang Li-Yun Zhang Xian Hu Wei-Qiang Tan |
| author_facet | Fa-Wei Xu Ying-Li Lv Yu-Fan Zhong Ya-Nan Xue Yong Wang Li-Yun Zhang Xian Hu Wei-Qiang Tan |
| author_sort | Fa-Wei Xu |
| collection | DOAJ |
| description | Epigallocatechin gallate (EGCG) is associated with various health benefits. In this review, we searched current work about the effects of EGCG and its wound dressings on skin for wound healing. Hydrogels, nanoparticles, micro/nanofiber networks and microneedles are the major types of EGCG-containing wound dressings. The beneficial effects of EGCG and its wound dressings at different stages of skin wound healing (hemostasis, inflammation, proliferation and tissue remodeling) were summarized based on the underlying mechanisms of antioxidant, anti-inflammatory, antimicrobial, angiogenesis and antifibrotic properties. This review expatiates on the rationale of using EGCG to promote skin wound healing and prevent scar formation, which provides a future clinical application direction of EGCG. |
| first_indexed | 2024-03-10T06:21:27Z |
| format | Article |
| id | doaj.art-c4909b119358487390d0455917cbcd0b |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-03-10T06:21:27Z |
| publishDate | 2021-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-c4909b119358487390d0455917cbcd0b2023-11-22T19:18:21ZengMDPI AGMolecules1420-30492021-10-012620612310.3390/molecules26206123Beneficial Effects of Green Tea EGCG on Skin Wound Healing: A Comprehensive ReviewFa-Wei Xu0Ying-Li Lv1Yu-Fan Zhong2Ya-Nan Xue3Yong Wang4Li-Yun Zhang5Xian Hu6Wei-Qiang Tan7Department of Plastic Surgery, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, 3 East Qingchun Road, Hangzhou 310016, ChinaTea Research Institute, College of Agriculture and Biotechnology, Zhejiang University, Hangzhou 310013, ChinaDepartment of Plastic Surgery, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, 3 East Qingchun Road, Hangzhou 310016, ChinaDepartment of Plastic Surgery, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, 3 East Qingchun Road, Hangzhou 310016, ChinaDepartment of Plastic Surgery, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, 3 East Qingchun Road, Hangzhou 310016, ChinaDepartment of Plastic Surgery, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, 3 East Qingchun Road, Hangzhou 310016, ChinaDepartment of Plastic Surgery, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, 3 East Qingchun Road, Hangzhou 310016, ChinaDepartment of Plastic Surgery, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, 3 East Qingchun Road, Hangzhou 310016, ChinaEpigallocatechin gallate (EGCG) is associated with various health benefits. In this review, we searched current work about the effects of EGCG and its wound dressings on skin for wound healing. Hydrogels, nanoparticles, micro/nanofiber networks and microneedles are the major types of EGCG-containing wound dressings. The beneficial effects of EGCG and its wound dressings at different stages of skin wound healing (hemostasis, inflammation, proliferation and tissue remodeling) were summarized based on the underlying mechanisms of antioxidant, anti-inflammatory, antimicrobial, angiogenesis and antifibrotic properties. This review expatiates on the rationale of using EGCG to promote skin wound healing and prevent scar formation, which provides a future clinical application direction of EGCG.https://www.mdpi.com/1420-3049/26/20/6123EGCGskin wound healingwound dressinganti-inflammationangiogenesisantifibrosis |
| spellingShingle | Fa-Wei Xu Ying-Li Lv Yu-Fan Zhong Ya-Nan Xue Yong Wang Li-Yun Zhang Xian Hu Wei-Qiang Tan Beneficial Effects of Green Tea EGCG on Skin Wound Healing: A Comprehensive Review Molecules EGCG skin wound healing wound dressing anti-inflammation angiogenesis antifibrosis |
| title | Beneficial Effects of Green Tea EGCG on Skin Wound Healing: A Comprehensive Review |
| title_full | Beneficial Effects of Green Tea EGCG on Skin Wound Healing: A Comprehensive Review |
| title_fullStr | Beneficial Effects of Green Tea EGCG on Skin Wound Healing: A Comprehensive Review |
| title_full_unstemmed | Beneficial Effects of Green Tea EGCG on Skin Wound Healing: A Comprehensive Review |
| title_short | Beneficial Effects of Green Tea EGCG on Skin Wound Healing: A Comprehensive Review |
| title_sort | beneficial effects of green tea egcg on skin wound healing a comprehensive review |
| topic | EGCG skin wound healing wound dressing anti-inflammation angiogenesis antifibrosis |
| url | https://www.mdpi.com/1420-3049/26/20/6123 |
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