Kidney damage phenylhydrazine and methods of its pathogenetic correction
In experiments on rats it was found that the administration of phenylhydrazine in doses of 10 mg, 50 mg and 100 mg / kg of body weight accompanied by a dose-dependent morphological damage of the kidneys. By comparing the morphological disorders in kidneys of rats were used for drinking tap water, 1...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Kazimierz Wielki University
2017-02-01
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| Series: | Journal of Education, Health and Sport |
| Subjects: | |
| Online Access: | https://apcz.umk.pl/JEHS/article/view/23955 |
| _version_ | 1818141033922297856 |
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| author | V M Sirman B A Nasibullin L M Shafran W Zukow A I Gozhenko |
| author_facet | V M Sirman B A Nasibullin L M Shafran W Zukow A I Gozhenko |
| author_sort | V M Sirman |
| collection | DOAJ |
| description |
In experiments on rats it was found that the administration of phenylhydrazine in doses of 10 mg, 50 mg and 100 mg / kg of body weight accompanied by a dose-dependent morphological damage of the kidneys. By comparing the morphological disorders in kidneys of rats were used for drinking tap water, 1% NaCl solution or a 0.75% NaCl and 0,36% NaHCO3 found that brines possess nephroprotective activity. The greatest protective effect with respect to kidney toxicity with phenylhydrazine possessed solution containing chloride and sodium bicarbonate.
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| first_indexed | 2024-12-11T10:53:27Z |
| format | Article |
| id | doaj.art-c4931dae3ce645db9f910cc613b2ad0c |
| institution | Directory Open Access Journal |
| issn | 2391-8306 |
| language | English |
| last_indexed | 2024-12-11T10:53:27Z |
| publishDate | 2017-02-01 |
| publisher | Kazimierz Wielki University |
| record_format | Article |
| series | Journal of Education, Health and Sport |
| spelling | doaj.art-c4931dae3ce645db9f910cc613b2ad0c2022-12-22T01:10:12ZengKazimierz Wielki UniversityJournal of Education, Health and Sport2391-83062017-02-0173Kidney damage phenylhydrazine and methods of its pathogenetic correctionV M Sirman0B A Nasibullin1L M Shafran2W Zukow3A I Gozhenko4Ukrainian Scientific and Research Institute of Transport Medicine of the Ministry of Health of UkraineUkrainian Scientific and Research Institute of Transport Medicine of the Ministry of Health of UkraineUkrainian Scientific and Research Institute of Transport Medicine of the Ministry of Health of UkraineFaculty of Physical Education, Health and Tourism, Kazimierz Wielki University, BydgoszczUkrainian Scientific and Research Institute of Transport Medicine of the Ministry of Health of Ukraine In experiments on rats it was found that the administration of phenylhydrazine in doses of 10 mg, 50 mg and 100 mg / kg of body weight accompanied by a dose-dependent morphological damage of the kidneys. By comparing the morphological disorders in kidneys of rats were used for drinking tap water, 1% NaCl solution or a 0.75% NaCl and 0,36% NaHCO3 found that brines possess nephroprotective activity. The greatest protective effect with respect to kidney toxicity with phenylhydrazine possessed solution containing chloride and sodium bicarbonate. https://apcz.umk.pl/JEHS/article/view/23955phenylhydrazinenephropathyrenoprotectionsodium chloridesodium bicarbonate. |
| spellingShingle | V M Sirman B A Nasibullin L M Shafran W Zukow A I Gozhenko Kidney damage phenylhydrazine and methods of its pathogenetic correction Journal of Education, Health and Sport phenylhydrazine nephropathy renoprotection sodium chloride sodium bicarbonate. |
| title | Kidney damage phenylhydrazine and methods of its pathogenetic correction |
| title_full | Kidney damage phenylhydrazine and methods of its pathogenetic correction |
| title_fullStr | Kidney damage phenylhydrazine and methods of its pathogenetic correction |
| title_full_unstemmed | Kidney damage phenylhydrazine and methods of its pathogenetic correction |
| title_short | Kidney damage phenylhydrazine and methods of its pathogenetic correction |
| title_sort | kidney damage phenylhydrazine and methods of its pathogenetic correction |
| topic | phenylhydrazine nephropathy renoprotection sodium chloride sodium bicarbonate. |
| url | https://apcz.umk.pl/JEHS/article/view/23955 |
| work_keys_str_mv | AT vmsirman kidneydamagephenylhydrazineandmethodsofitspathogeneticcorrection AT banasibullin kidneydamagephenylhydrazineandmethodsofitspathogeneticcorrection AT lmshafran kidneydamagephenylhydrazineandmethodsofitspathogeneticcorrection AT wzukow kidneydamagephenylhydrazineandmethodsofitspathogeneticcorrection AT aigozhenko kidneydamagephenylhydrazineandmethodsofitspathogeneticcorrection |