Neosaxitoxin Inhibits the Expression of Inflammation Markers of the M1 Phenotype in Macrophages

Neosaxitoxin Inhibits the Expression of Inflammation Markers of the M1 Phenotype in Macrophages

(1) Background: Neosaxitoxin (NeoSTX) has been used as a local anesthetic, but its anti-inflammatory effects have not been well defined. In the present study, we investigate the effects of NeoSTX on lipopolysaccharide (LPS)-activated macrophages. (2) Methods: Raw 264.7 and equine PBMC cells were inc...

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Bibliographic Details
Main Authors: M. Cecilia Montero, Miguel del Campo, M. Bono, M. Valeska Simon, Julia Guerrero, Néstor Lagos
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Marine Drugs
Subjects:
neosaxitoxin
inflammation
Nav channels
macrophages
Online Access:https://www.mdpi.com/1660-3397/18/6/283

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