Enzymatic systems involved in D-limonene biooxidation

The biooxidation of limonene by an Aspergillus strain resulted in the production of perillyl alcohol and short chain fatty acids. Addition of ketoconazole, a known inhibitor of cytochrome P450 oxydase, eliminated the production of free acids, but did not affect biotransformation to perillyl alcohol....

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Bibliographic Details
Main Authors: Pilar Menéndez, Carlos García, Paula Rodríguez, Patrick Moyna, Horacio Heinzen
Format: Article
Language:English
Published: Instituto de Tecnologia do Paraná (Tecpar) 2002-06-01
Series:Brazilian Archives of Biology and Technology
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Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132002000200001
Description
Summary:The biooxidation of limonene by an Aspergillus strain resulted in the production of perillyl alcohol and short chain fatty acids. Addition of ketoconazole, a known inhibitor of cytochrome P450 oxydase, eliminated the production of free acids, but did not affect biotransformation to perillyl alcohol.<br>A biooxidação do limoneno por uma linhagem de Aspergillus resulta na produção de álcool perílico e ácidos graxos de cadeia curta. A adição de quetoconazol, um conhecido inibidor da citocromo P450 oxidase, elimina a produção de ácidos graxos livres, mas não afeta a biotransformação a álcool perilhílico.
ISSN:1516-8913
1678-4324