LncRNA XIST restrains the activation of Müller cells and inflammation in diabetic retinopathy via stabilizing SIRT1

LncRNA XIST restrains the activation of Müller cells and inflammation in diabetic retinopathy via stabilizing SIRT1

Background Recent studies have provided strong evidence that lncRNAs play a functional regulatory role in diabetic retinopathy (DR). The purpose of this study was to investigate the effect of long non-coding RNA (lncRNA) X-inactive specific transcript (XIST) in DR. Methods A DR mouse model was estab...

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Bibliographic Details
Main Authors: Jiayu Zhang, Chengwei Chen, Sifang Zhang, Jiawei Chen, Liang Wu, Zhenguo Chen
Format: Article
Language:English
Published: Taylor & Francis Group 2021-11-01
Series:Autoimmunity
Subjects:
lncrna xist
sirt1
müller cells
diabetic retinopathy (dr)
pro-inflammatory cytokines
Online Access:http://dx.doi.org/10.1080/08916934.2021.1969551

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