Carpal Tunnel Syndrome and Diabetes—A Comprehensive Review
Carpal tunnel syndrome (CTS) is the most common compression neuropathy in the general population and is frequently encountered among individuals with type 1 and 2 diabetes. The reason(s) why a peripheral nerve trunk in individuals with diabetes is more susceptible to nerve compression is still not c...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-03-01
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| Series: | Journal of Clinical Medicine |
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| Online Access: | https://www.mdpi.com/2077-0383/11/6/1674 |
| _version_ | 1797470483593035776 |
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| author | Malin Zimmerman Anders Gottsäter Lars B. Dahlin |
| author_facet | Malin Zimmerman Anders Gottsäter Lars B. Dahlin |
| author_sort | Malin Zimmerman |
| collection | DOAJ |
| description | Carpal tunnel syndrome (CTS) is the most common compression neuropathy in the general population and is frequently encountered among individuals with type 1 and 2 diabetes. The reason(s) why a peripheral nerve trunk in individuals with diabetes is more susceptible to nerve compression is still not completely clarified, but both biochemical and structural changes in the peripheral nerve are probably implicated. In particular, individuals with neuropathy, irrespective of aetiology, have a higher risk of peripheral nerve compression disorders, as reflected among individuals with diabetic neuropathy. Diagnosis of CTS in individuals with diabetes should be carefully evaluated; detailed case history, thorough clinical examination, and electrophysiological examination is recommended. Individuals with diabetes and CTS benefit from surgery to the same extent as otherwise healthy individuals with CTS. In the present review, we describe pathophysiological aspects of the nerve compression disorder CTS in relation to diabetes, current data contributing to the explanation of the increased risk for CTS in individuals with diabetes, as well as diagnostic methods, treatment options, and prognosis of CTS in diabetes. |
| first_indexed | 2024-03-09T19:37:53Z |
| format | Article |
| id | doaj.art-c49938dfa9a44c3c885a8b1db6d1a267 |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-09T19:37:53Z |
| publishDate | 2022-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-c49938dfa9a44c3c885a8b1db6d1a2672023-11-24T01:50:36ZengMDPI AGJournal of Clinical Medicine2077-03832022-03-01116167410.3390/jcm11061674Carpal Tunnel Syndrome and Diabetes—A Comprehensive ReviewMalin Zimmerman0Anders Gottsäter1Lars B. Dahlin2Department of Hand Surgery, Skåne University Hospital, Lund University, 205 02 Malmö, SwedenDepartment of Medicine, Skåne University Hospital, 205 02 Malmö, SwedenDepartment of Hand Surgery, Skåne University Hospital, Lund University, 205 02 Malmö, SwedenCarpal tunnel syndrome (CTS) is the most common compression neuropathy in the general population and is frequently encountered among individuals with type 1 and 2 diabetes. The reason(s) why a peripheral nerve trunk in individuals with diabetes is more susceptible to nerve compression is still not completely clarified, but both biochemical and structural changes in the peripheral nerve are probably implicated. In particular, individuals with neuropathy, irrespective of aetiology, have a higher risk of peripheral nerve compression disorders, as reflected among individuals with diabetic neuropathy. Diagnosis of CTS in individuals with diabetes should be carefully evaluated; detailed case history, thorough clinical examination, and electrophysiological examination is recommended. Individuals with diabetes and CTS benefit from surgery to the same extent as otherwise healthy individuals with CTS. In the present review, we describe pathophysiological aspects of the nerve compression disorder CTS in relation to diabetes, current data contributing to the explanation of the increased risk for CTS in individuals with diabetes, as well as diagnostic methods, treatment options, and prognosis of CTS in diabetes.https://www.mdpi.com/2077-0383/11/6/1674carpal tunnel syndromediabetic neuropathydiabetes |
| spellingShingle | Malin Zimmerman Anders Gottsäter Lars B. Dahlin Carpal Tunnel Syndrome and Diabetes—A Comprehensive Review Journal of Clinical Medicine carpal tunnel syndrome diabetic neuropathy diabetes |
| title | Carpal Tunnel Syndrome and Diabetes—A Comprehensive Review |
| title_full | Carpal Tunnel Syndrome and Diabetes—A Comprehensive Review |
| title_fullStr | Carpal Tunnel Syndrome and Diabetes—A Comprehensive Review |
| title_full_unstemmed | Carpal Tunnel Syndrome and Diabetes—A Comprehensive Review |
| title_short | Carpal Tunnel Syndrome and Diabetes—A Comprehensive Review |
| title_sort | carpal tunnel syndrome and diabetes a comprehensive review |
| topic | carpal tunnel syndrome diabetic neuropathy diabetes |
| url | https://www.mdpi.com/2077-0383/11/6/1674 |
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