De Novo Design of AC-P19M, a Novel Anticancer Peptide with Apoptotic Effects on Lung Cancer Cells and Anti-Angiogenic Activity

De Novo Design of AC-P19M, a Novel Anticancer Peptide with Apoptotic Effects on Lung Cancer Cells and Anti-Angiogenic Activity

Despite the current developments in cancer therapeutics, efforts to excavate new anticancer agents continue rigorously due to obstacles, such as side effects and drug resistance. Anticancer peptides (ACPs) can be utilized to treat cancer because of their effectiveness on a variety of molecular targe...

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Bibliographic Details
Main Authors: Min Kyoung Shin, Bo-Young Jang, Kyung-Bin Bu, Seung-Ho Lee, Dong-Hee Han, Jin Wook Oh, Jung-Suk Sung
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:International Journal of Molecular Sciences
Subjects:
anticancer peptide (ACP)
in silico analysis
cell lysis
apoptosis
EMT inhibition
anti-angiogenic
Online Access:https://www.mdpi.com/1422-0067/23/24/15594

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