A Comparison of Maternal and Fetal Outcomes of Pregnancies Complicated by Moderate to Severe Thrombocytopenia Caused by Gestational Thrombocytopenia Preeclampsia / HELLP Syndrome and Immune Thrombocytopenic Purpura

OBJECTIVE: Aim of this study was to compare obstetric risk factors and complications, and outcomes of pregnancies associated with moderate to severe thrombocytopenia caused by gestational thrombocytopenia (GT), preeclampsia/HELLP syndrome, and immune thrombocytopenic purpura (ITP). STUDY DESIGN: The...

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Bibliographic Details
Main Authors: Suna Özdemir, Hüseyin Görkemli, Ali Acar, Çetin Çelik, Erkan Kayıkçıoğlu
Format: Article
Language:English
Published: Medical Network 2008-12-01
Series:Gynecology Obstetrics & Reproductive Medicine
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Online Access:http://gorm.com.tr/index.php/GORM/article/view/462
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Summary:OBJECTIVE: Aim of this study was to compare obstetric risk factors and complications, and outcomes of pregnancies associated with moderate to severe thrombocytopenia caused by gestational thrombocytopenia (GT), preeclampsia/HELLP syndrome, and immune thrombocytopenic purpura (ITP). STUDY DESIGN: The study was composed of 135 women with a platelet count below 100.000/mm3. The characteristics and clinical details of all women and neonatal were recorded during their hospital course. RESULTS: The ratio of severe thrombocytopenia was observed significantly lower in GT group compared with preeclampsia / HELLP syndrome and ITP groups. Higher rates of oligohydroamnios, IUGR, and placental abruption were found among patients in preeclampsia+HELLP syndrome group. The rates of Apgar scores (<7) at 1 and 5 min, pH values (<7,2), and amniotic fluid with meconium were higher in preeclampsia / HELLP syndrome group. Neonatal thrombocytopenia was recorded in a total of 5 infants. CONCLUSION: The thrombocytopenia with preeclampsia/HELLP syndrome had less favorable obstetric and fetal outcomes.
ISSN:1300-4751