Liposomal Artificial Red Blood Cell-Based Carbon Monoxide Donor Is a Potent Renoprotectant against Cisplatin-Induced Acute Kidney Injury

Liposomal Artificial Red Blood Cell-Based Carbon Monoxide Donor Is a Potent Renoprotectant against Cisplatin-Induced Acute Kidney Injury

Cisplatin (CDDP) is an essential anti-tumor agent for chemotherapeutic regimens against various types of cancer. However, the progression of nephrotoxicity, which is the main adverse effect of CDDP, leads to discontinuation of CDDP chemotherapy. Therefore, development of a renoprotectant against CDD...

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Bibliographic Details
Main Authors: Kazuaki Taguchi, Yuto Suzuki, Moeko Tsutsuura, Kana Hiraoka, Yuki Watabe, Yuki Enoki, Masaki Otagiri, Hiromi Sakai, Kazuaki Matsumoto
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Pharmaceutics
Subjects:
cisplatin
nephrotoxicity
liposome
artificial blood
carbon monoxide
apoptosis
Online Access:https://www.mdpi.com/1999-4923/14/1/57

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