Impact of Surgical Intervention on Nonobstructive Dysphagia: A Retrospective Study Based on High-Resolution Impedance Manometry in a Taiwanese Population at a Single Institution
Esophageal motility disorders account for a large proportion of nonobstructive dysphagia cases, which constitute a heterogeneous group of diagnoses that commonly result in peristaltic derangement and impaired relaxation of the lower esophageal sphincter. We performed a single-institution retrospecti...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-04-01
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| Series: | Journal of Personalized Medicine |
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| Online Access: | https://www.mdpi.com/2075-4426/12/4/590 |
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| author | Gang-Hua Lin Kuan-Hsun Lin Szu-Yu Lin Tsai-Wang Huang Hung Chang Hsu-Kai Huang |
| author_facet | Gang-Hua Lin Kuan-Hsun Lin Szu-Yu Lin Tsai-Wang Huang Hung Chang Hsu-Kai Huang |
| author_sort | Gang-Hua Lin |
| collection | DOAJ |
| description | Esophageal motility disorders account for a large proportion of nonobstructive dysphagia cases, which constitute a heterogeneous group of diagnoses that commonly result in peristaltic derangement and impaired relaxation of the lower esophageal sphincter. We performed a single-institution retrospective study enrolling consecutive patients with chief complaints of dysphagia who underwent HRIM from December 2014 to December 2019, and analyzed demographic, clinical, and manometric data using descriptive statistics. In total, 277 identified patients were included in the final analysis. Ineffective esophageal motility (<i>n</i> = 152, 24.5%) was the most common diagnosis by HRIM, followed by absent contractility, EGJ outflow obstruction, type II achalasia, and type I achalasia. Furthermore, surgery including exploratory, laparoscopic, and robotic myotomy, as well as POEM, is considered the most effective treatment for patients with non-spastic achalasia and EGJOO, due to its effective symptom palliation and prevention of disease progression; surgery also contributes to an obvious improvement of dysphagia compared with slightly less efficacy for other related symptoms. Our study aimed to elaborate the clinical characteristics of patients with nonobstructive dysphagia based on HRIM in a Taiwanese population, and to analyze the therapeutic outcomes of such patients who ultimately underwent surgical interventions. |
| first_indexed | 2024-03-09T13:27:36Z |
| format | Article |
| id | doaj.art-c4a7086839e745a48757ca16cd21bc3d |
| institution | Directory Open Access Journal |
| issn | 2075-4426 |
| language | English |
| last_indexed | 2024-03-09T13:27:36Z |
| publishDate | 2022-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Personalized Medicine |
| spelling | doaj.art-c4a7086839e745a48757ca16cd21bc3d2023-11-30T21:22:52ZengMDPI AGJournal of Personalized Medicine2075-44262022-04-0112459010.3390/jpm12040590Impact of Surgical Intervention on Nonobstructive Dysphagia: A Retrospective Study Based on High-Resolution Impedance Manometry in a Taiwanese Population at a Single InstitutionGang-Hua Lin0Kuan-Hsun Lin1Szu-Yu Lin2Tsai-Wang Huang3Hung Chang4Hsu-Kai Huang5Department of Surgery, Tri-Service General Hospital, National Defense Medical Center, Taipei 114, TaiwanDivision of Thoracic Surgery, Department of Surgery, Tri-Service General Hospital, National Defense Medical Center, Taipei 114, TaiwanCritical Care Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei 114, TaiwanDivision of Thoracic Surgery, Department of Surgery, Tri-Service General Hospital, National Defense Medical Center, Taipei 114, TaiwanDivision of Thoracic Surgery, Department of Surgery, Tri-Service General Hospital, National Defense Medical Center, Taipei 114, TaiwanDivision of Thoracic Surgery, Department of Surgery, Tri-Service General Hospital, National Defense Medical Center, Taipei 114, TaiwanEsophageal motility disorders account for a large proportion of nonobstructive dysphagia cases, which constitute a heterogeneous group of diagnoses that commonly result in peristaltic derangement and impaired relaxation of the lower esophageal sphincter. We performed a single-institution retrospective study enrolling consecutive patients with chief complaints of dysphagia who underwent HRIM from December 2014 to December 2019, and analyzed demographic, clinical, and manometric data using descriptive statistics. In total, 277 identified patients were included in the final analysis. Ineffective esophageal motility (<i>n</i> = 152, 24.5%) was the most common diagnosis by HRIM, followed by absent contractility, EGJ outflow obstruction, type II achalasia, and type I achalasia. Furthermore, surgery including exploratory, laparoscopic, and robotic myotomy, as well as POEM, is considered the most effective treatment for patients with non-spastic achalasia and EGJOO, due to its effective symptom palliation and prevention of disease progression; surgery also contributes to an obvious improvement of dysphagia compared with slightly less efficacy for other related symptoms. Our study aimed to elaborate the clinical characteristics of patients with nonobstructive dysphagia based on HRIM in a Taiwanese population, and to analyze the therapeutic outcomes of such patients who ultimately underwent surgical interventions.https://www.mdpi.com/2075-4426/12/4/590high-resolution impedance manometryachalasiaesophagogastric junction outflow obstructionChicago ClassificationEckardt score |
| spellingShingle | Gang-Hua Lin Kuan-Hsun Lin Szu-Yu Lin Tsai-Wang Huang Hung Chang Hsu-Kai Huang Impact of Surgical Intervention on Nonobstructive Dysphagia: A Retrospective Study Based on High-Resolution Impedance Manometry in a Taiwanese Population at a Single Institution Journal of Personalized Medicine high-resolution impedance manometry achalasia esophagogastric junction outflow obstruction Chicago Classification Eckardt score |
| title | Impact of Surgical Intervention on Nonobstructive Dysphagia: A Retrospective Study Based on High-Resolution Impedance Manometry in a Taiwanese Population at a Single Institution |
| title_full | Impact of Surgical Intervention on Nonobstructive Dysphagia: A Retrospective Study Based on High-Resolution Impedance Manometry in a Taiwanese Population at a Single Institution |
| title_fullStr | Impact of Surgical Intervention on Nonobstructive Dysphagia: A Retrospective Study Based on High-Resolution Impedance Manometry in a Taiwanese Population at a Single Institution |
| title_full_unstemmed | Impact of Surgical Intervention on Nonobstructive Dysphagia: A Retrospective Study Based on High-Resolution Impedance Manometry in a Taiwanese Population at a Single Institution |
| title_short | Impact of Surgical Intervention on Nonobstructive Dysphagia: A Retrospective Study Based on High-Resolution Impedance Manometry in a Taiwanese Population at a Single Institution |
| title_sort | impact of surgical intervention on nonobstructive dysphagia a retrospective study based on high resolution impedance manometry in a taiwanese population at a single institution |
| topic | high-resolution impedance manometry achalasia esophagogastric junction outflow obstruction Chicago Classification Eckardt score |
| url | https://www.mdpi.com/2075-4426/12/4/590 |
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