Sphingosine-1-Phosphate and Macrophage Biology—How the Sphinx Tames the Big Eater
The sphingolipid sphingosine-1-phosphate (S1P) is produced by sphingosine kinases to either signal through intracellular targets or to activate a family of specific G-protein-coupled receptors (S1PR). S1P levels are usually low in peripheral tissues compared to the vasculature, forming a gradient th...
| Main Authors: | , , |
|---|---|
| 格式: | 文件 |
| 语言: | English |
| 出版: |
Frontiers Media S.A.
2019-07-01
|
| 丛编: | Frontiers in Immunology |
| 主题: | |
| 在线阅读: | https://www.frontiersin.org/article/10.3389/fimmu.2019.01706/full |