Treating Neurogenic Lower Urinary Tract Dysfunction in Chronic Spinal Cord Injury Patients—When Intravesical Botox Injection or Urethral Botox Injection Are Indicated
Lower urinary tract symptoms (LUTS), such as urgency, urinary incontinence, and/or difficulty voiding, hamper the quality of life (QoL) of patients with spinal cord injury (SCI). If not managed adequately, urological complications, such as urinary tract infection or renal function deterioration, may...
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MDPI AG
2023-04-01
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author | Po-Cheng Chen Kau-Han Lee Wei-Chia Lee Ting-Chun Yeh Yuh-Chen Kuo Bing-Juin Chiang Chun-Hou Liao En Meng Yao-Lin Kao Yung-Chin Lee Hann-Chorng Kuo |
author_facet | Po-Cheng Chen Kau-Han Lee Wei-Chia Lee Ting-Chun Yeh Yuh-Chen Kuo Bing-Juin Chiang Chun-Hou Liao En Meng Yao-Lin Kao Yung-Chin Lee Hann-Chorng Kuo |
author_sort | Po-Cheng Chen |
collection | DOAJ |
description | Lower urinary tract symptoms (LUTS), such as urgency, urinary incontinence, and/or difficulty voiding, hamper the quality of life (QoL) of patients with spinal cord injury (SCI). If not managed adequately, urological complications, such as urinary tract infection or renal function deterioration, may further deteriorate the patient’s QoL. Botulinum toxin A (BoNT-A) injection within the detrusor muscle or urethral sphincter yields satisfactory therapeutic effects for treating urinary incontinence or facilitating efficient voiding; however, adverse effects inevitably follow its therapeutic efficacy. It is important to weigh the merits and demerits of BoNT-A injection for LUTS and provide an optimal management strategy for SCI patients. This paper summarizes different aspects of the application of BoNT-A injection for lower urinary tract dysfunctions in SCI patients and provides an overview of the benefits and drawbacks of this treatment. |
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issn | 2072-6651 |
language | English |
last_indexed | 2024-03-11T04:28:25Z |
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spelling | doaj.art-c4acca96eea946d5a65fbe453a75462d2023-11-17T21:39:04ZengMDPI AGToxins2072-66512023-04-0115428810.3390/toxins15040288Treating Neurogenic Lower Urinary Tract Dysfunction in Chronic Spinal Cord Injury Patients—When Intravesical Botox Injection or Urethral Botox Injection Are IndicatedPo-Cheng Chen0Kau-Han Lee1Wei-Chia Lee2Ting-Chun Yeh3Yuh-Chen Kuo4Bing-Juin Chiang5Chun-Hou Liao6En Meng7Yao-Lin Kao8Yung-Chin Lee9Hann-Chorng Kuo10Urologic Department, En Chu Kong Hospital, New Taipei City 237414, TaiwanDivision of Urology, Department of Surgery, Chi Mei Medical Center, Tainan 71004, TaiwanDepartment of Urology, Kaohsiung Chang Gung Memorial Hospital, College of Medicine, Chang Gung University, Taoyuan 33302, TaiwanDivision of Urology, Department of Surgery, Taiwan Adventist Hospital, Taipei City 10556, TaiwanDepartment of Urology, Yangming Branch of Taipei City Hospital, Taipei 11146, TaiwanCollege of Medicine, Fu-Jen Catholic University, New Taipei City 24205, TaiwanDivisions of Urology, Department of Surgery, Cardinal Tien Hospital, New Taipei City 23148, TaiwanDivision of Urology, Department of Surgery, Tri-Service General Hospital, National Defense Medical Center, Taipei 11490, TaiwanDepartment of Urology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan 704, TaiwanDepartment of Urology, Kaohsiung Municipal Siaogang Hospital, Kaohsiung 812, TaiwanDepartment of Urology, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation and Tzu Chi University, Hualien 97004, TaiwanLower urinary tract symptoms (LUTS), such as urgency, urinary incontinence, and/or difficulty voiding, hamper the quality of life (QoL) of patients with spinal cord injury (SCI). If not managed adequately, urological complications, such as urinary tract infection or renal function deterioration, may further deteriorate the patient’s QoL. Botulinum toxin A (BoNT-A) injection within the detrusor muscle or urethral sphincter yields satisfactory therapeutic effects for treating urinary incontinence or facilitating efficient voiding; however, adverse effects inevitably follow its therapeutic efficacy. It is important to weigh the merits and demerits of BoNT-A injection for LUTS and provide an optimal management strategy for SCI patients. This paper summarizes different aspects of the application of BoNT-A injection for lower urinary tract dysfunctions in SCI patients and provides an overview of the benefits and drawbacks of this treatment.https://www.mdpi.com/2072-6651/15/4/288spinal cord injurybotulinum toxinslower urinary tract symptoms |
spellingShingle | Po-Cheng Chen Kau-Han Lee Wei-Chia Lee Ting-Chun Yeh Yuh-Chen Kuo Bing-Juin Chiang Chun-Hou Liao En Meng Yao-Lin Kao Yung-Chin Lee Hann-Chorng Kuo Treating Neurogenic Lower Urinary Tract Dysfunction in Chronic Spinal Cord Injury Patients—When Intravesical Botox Injection or Urethral Botox Injection Are Indicated Toxins spinal cord injury botulinum toxins lower urinary tract symptoms |
title | Treating Neurogenic Lower Urinary Tract Dysfunction in Chronic Spinal Cord Injury Patients—When Intravesical Botox Injection or Urethral Botox Injection Are Indicated |
title_full | Treating Neurogenic Lower Urinary Tract Dysfunction in Chronic Spinal Cord Injury Patients—When Intravesical Botox Injection or Urethral Botox Injection Are Indicated |
title_fullStr | Treating Neurogenic Lower Urinary Tract Dysfunction in Chronic Spinal Cord Injury Patients—When Intravesical Botox Injection or Urethral Botox Injection Are Indicated |
title_full_unstemmed | Treating Neurogenic Lower Urinary Tract Dysfunction in Chronic Spinal Cord Injury Patients—When Intravesical Botox Injection or Urethral Botox Injection Are Indicated |
title_short | Treating Neurogenic Lower Urinary Tract Dysfunction in Chronic Spinal Cord Injury Patients—When Intravesical Botox Injection or Urethral Botox Injection Are Indicated |
title_sort | treating neurogenic lower urinary tract dysfunction in chronic spinal cord injury patients when intravesical botox injection or urethral botox injection are indicated |
topic | spinal cord injury botulinum toxins lower urinary tract symptoms |
url | https://www.mdpi.com/2072-6651/15/4/288 |
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