Fibroblastic rheumatism treated with methotrexate and colchicine
Objective: Fibroblastic rheumatism (FR) is a rare disease first described by Chaouat in 1980 which is characterized by a combination of rheumatologic and dermatological manifestations. Rheumatologic features are symmetrical polyarthralgia with joint stiffness, associated with cutaneous nodules and s...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Verduci Editore
2023-07-01
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| Series: | Beyond Rheumatology |
| Subjects: | |
| Online Access: | https://www.beyond-rheumatology.org/wp-content/uploads/sites/10/2023/07/e477.pdf |
| _version_ | 1797780562736316416 |
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| author | J. de Carvalho P. Criado |
| author_facet | J. de Carvalho P. Criado |
| author_sort | J. de Carvalho |
| collection | DOAJ |
| description | Objective: Fibroblastic rheumatism (FR) is a rare disease first described by Chaouat in 1980 which is characterized by a combination of rheumatologic and dermatological manifestations. Rheumatologic features are symmetrical polyarthralgia with joint stiffness, associated with cutaneous nodules and sclerodactyly. Histology shows an increased number of fibroblasts and marked dermal fibrosis. In this report, we described a rare cutaneous disease-fibroblastic rheumatism, in which the patient had an excellent response to methotrexate associated with colchicine.
Case Presentation: A 13 years old boy who was previously healthy started in 2013 deformities over his fingers without pain or any inflammatory signs associated with joint stiffness. This is the second Brazilian case of FR treated with methotrexate and colchicine.
Conclusions: The patient observed a slight improvement in cutaneous nodules and joint stiffness. Though FR is a rare disease, early diagnosis is mandatory. This case reinforces that MTX associated with colchicine may be an additional therapeutic tool for these patients. |
| first_indexed | 2024-03-12T23:45:41Z |
| format | Article |
| id | doaj.art-c4af7931939346988dcebf3a9a643a0f |
| institution | Directory Open Access Journal |
| issn | 2612-5110 |
| language | English |
| last_indexed | 2024-03-12T23:45:41Z |
| publishDate | 2023-07-01 |
| publisher | Verduci Editore |
| record_format | Article |
| series | Beyond Rheumatology |
| spelling | doaj.art-c4af7931939346988dcebf3a9a643a0f2023-07-14T10:14:51ZengVerduci EditoreBeyond Rheumatology2612-51102023-07-01510.53238/br_20237_477477Fibroblastic rheumatism treated with methotrexate and colchicineJ. de Carvalho0P. Criado1Institute for Health Sciences from Federal University of Bahia, Salvador, Bahia, BrazilFaculdade de Medicina do ABC, Santo Andrè, BrazilObjective: Fibroblastic rheumatism (FR) is a rare disease first described by Chaouat in 1980 which is characterized by a combination of rheumatologic and dermatological manifestations. Rheumatologic features are symmetrical polyarthralgia with joint stiffness, associated with cutaneous nodules and sclerodactyly. Histology shows an increased number of fibroblasts and marked dermal fibrosis. In this report, we described a rare cutaneous disease-fibroblastic rheumatism, in which the patient had an excellent response to methotrexate associated with colchicine. Case Presentation: A 13 years old boy who was previously healthy started in 2013 deformities over his fingers without pain or any inflammatory signs associated with joint stiffness. This is the second Brazilian case of FR treated with methotrexate and colchicine. Conclusions: The patient observed a slight improvement in cutaneous nodules and joint stiffness. Though FR is a rare disease, early diagnosis is mandatory. This case reinforces that MTX associated with colchicine may be an additional therapeutic tool for these patients.https://www.beyond-rheumatology.org/wp-content/uploads/sites/10/2023/07/e477.pdffibroblastic rheumatismcutaneous nodulesfibrosispeyronie's diseasemethotrexatecolchicine |
| spellingShingle | J. de Carvalho P. Criado Fibroblastic rheumatism treated with methotrexate and colchicine Beyond Rheumatology fibroblastic rheumatism cutaneous nodules fibrosis peyronie's disease methotrexate colchicine |
| title | Fibroblastic rheumatism treated with methotrexate and colchicine |
| title_full | Fibroblastic rheumatism treated with methotrexate and colchicine |
| title_fullStr | Fibroblastic rheumatism treated with methotrexate and colchicine |
| title_full_unstemmed | Fibroblastic rheumatism treated with methotrexate and colchicine |
| title_short | Fibroblastic rheumatism treated with methotrexate and colchicine |
| title_sort | fibroblastic rheumatism treated with methotrexate and colchicine |
| topic | fibroblastic rheumatism cutaneous nodules fibrosis peyronie's disease methotrexate colchicine |
| url | https://www.beyond-rheumatology.org/wp-content/uploads/sites/10/2023/07/e477.pdf |
| work_keys_str_mv | AT jdecarvalho fibroblasticrheumatismtreatedwithmethotrexateandcolchicine AT pcriado fibroblasticrheumatismtreatedwithmethotrexateandcolchicine |