GATED SPECT IN PATIENTS WITH BIOPSY-NEGATIVE CARDIAC TRANSPLANT REJECTION

Humoral rejection of the cardiac allograft is still a challenging problem associated with high incidence of graft loss and patient mortality. These episodes of rejection are often more severe, and more difficult to treat, than classical acute cellular rejection. Hemodynamic compromise, in the absenc...

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Main Authors: E. N. Ostroumov, V. M. Zakharevich, E. D. Kotina, N. N. Mojeiko, A. G. Kupriyanova, E. I. Ryaboshtanova, B. N. Morozov, N. Z. Meboniya, S. V. Mironov, A. Y. Kormer, I. M. Ilynsky, L. V. Beletskaya, E. N. Kazakov
Format: Article
Language:Russian
Published: Federal Research Center of Transplantology and Artificial Organs named after V.I.Shumakov 2009-05-01
Series:Vestnik Transplantologii i Iskusstvennyh Organov
Subjects:
Online Access:https://journal.transpl.ru/vtio/article/view/247
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author E. N. Ostroumov
V. M. Zakharevich
E. D. Kotina
N. N. Mojeiko
A. G. Kupriyanova
E. I. Ryaboshtanova
B. N. Morozov
N. Z. Meboniya
S. V. Mironov
A. Y. Kormer
I. M. Ilynsky
L. V. Beletskaya
E. N. Kazakov
author_facet E. N. Ostroumov
V. M. Zakharevich
E. D. Kotina
N. N. Mojeiko
A. G. Kupriyanova
E. I. Ryaboshtanova
B. N. Morozov
N. Z. Meboniya
S. V. Mironov
A. Y. Kormer
I. M. Ilynsky
L. V. Beletskaya
E. N. Kazakov
author_sort E. N. Ostroumov
collection DOAJ
description Humoral rejection of the cardiac allograft is still a challenging problem associated with high incidence of graft loss and patient mortality. These episodes of rejection are often more severe, and more difficult to treat, than classical acute cellular rejection. Hemodynamic compromise, in the absence of acute cellular rejection, called biopsy-negative rejection occurs in 10 to 20% of cardiac allograft recipients. The assessment of hemodynamic compromise can provide functional data in transplant patients that is complementary to myocardial biopsies if the biopsy can miss significant rejection. We present three cases of the biopsy-negative rejection. All patients have studied with gated SPECT phase analysis.
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spelling doaj.art-c4b038a5450348509c15e7f279fb2fc42023-03-13T10:37:19ZrusFederal Research Center of Transplantology and Artificial Organs named after V.I.ShumakovVestnik Transplantologii i Iskusstvennyh Organov1995-11912009-05-01113626810.15825/1995-1191-2009-3-62-68190GATED SPECT IN PATIENTS WITH BIOPSY-NEGATIVE CARDIAC TRANSPLANT REJECTIONE. N. Ostroumov0V. M. Zakharevich1E. D. Kotina2N. N. Mojeiko3A. G. Kupriyanova4E. I. Ryaboshtanova5B. N. Morozov6N. Z. Meboniya7S. V. Mironov8A. Y. Kormer9I. M. Ilynsky10L. V. Beletskaya11E. N. Kazakov12Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, MoscowAcademician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, MoscowSaint-Petersburg State University, Saint-PetersburgAcademician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, MoscowAcademician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, MoscowAcademician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, MoscowAcademician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, MoscowAcademician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, MoscowAcademician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, MoscowAcademician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, MoscowAcademician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, MoscowAcademician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, MoscowAcademician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, MoscowHumoral rejection of the cardiac allograft is still a challenging problem associated with high incidence of graft loss and patient mortality. These episodes of rejection are often more severe, and more difficult to treat, than classical acute cellular rejection. Hemodynamic compromise, in the absence of acute cellular rejection, called biopsy-negative rejection occurs in 10 to 20% of cardiac allograft recipients. The assessment of hemodynamic compromise can provide functional data in transplant patients that is complementary to myocardial biopsies if the biopsy can miss significant rejection. We present three cases of the biopsy-negative rejection. All patients have studied with gated SPECT phase analysis.https://journal.transpl.ru/vtio/article/view/247cardiac transplantationhumoral rejectionnon-cellular rejectionbiopsy-negative rejectiongated spect
spellingShingle E. N. Ostroumov
V. M. Zakharevich
E. D. Kotina
N. N. Mojeiko
A. G. Kupriyanova
E. I. Ryaboshtanova
B. N. Morozov
N. Z. Meboniya
S. V. Mironov
A. Y. Kormer
I. M. Ilynsky
L. V. Beletskaya
E. N. Kazakov
GATED SPECT IN PATIENTS WITH BIOPSY-NEGATIVE CARDIAC TRANSPLANT REJECTION
Vestnik Transplantologii i Iskusstvennyh Organov
cardiac transplantation
humoral rejection
non-cellular rejection
biopsy-negative rejection
gated spect
title GATED SPECT IN PATIENTS WITH BIOPSY-NEGATIVE CARDIAC TRANSPLANT REJECTION
title_full GATED SPECT IN PATIENTS WITH BIOPSY-NEGATIVE CARDIAC TRANSPLANT REJECTION
title_fullStr GATED SPECT IN PATIENTS WITH BIOPSY-NEGATIVE CARDIAC TRANSPLANT REJECTION
title_full_unstemmed GATED SPECT IN PATIENTS WITH BIOPSY-NEGATIVE CARDIAC TRANSPLANT REJECTION
title_short GATED SPECT IN PATIENTS WITH BIOPSY-NEGATIVE CARDIAC TRANSPLANT REJECTION
title_sort gated spect in patients with biopsy negative cardiac transplant rejection
topic cardiac transplantation
humoral rejection
non-cellular rejection
biopsy-negative rejection
gated spect
url https://journal.transpl.ru/vtio/article/view/247
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