Gut microbiome and its association with psychiatric disorders, specially schizophrenia

Background and Aim: Microorganisms living in the human body play an important role in human health. Human microbiota is known as an essential agent and playing an important role in the biological processes of the human body. The role of the microbiota in the host metabolism, intestinal inflammatory...

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Main Authors: Faria Hasanzadeh Haghighi, Bamdad Riahi-Zanjani, Ehsan Aryan
Format: Article
Language:fas
Published: Kurdistan University of Medical Sciences 2023-05-01
Series:مجله علمی دانشگاه علوم پزشکی کردستان
Subjects:
Online Access:http://sjku.muk.ac.ir/article-1-7929-en.pdf
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author Faria Hasanzadeh Haghighi
Bamdad Riahi-Zanjani
Ehsan Aryan
author_facet Faria Hasanzadeh Haghighi
Bamdad Riahi-Zanjani
Ehsan Aryan
author_sort Faria Hasanzadeh Haghighi
collection DOAJ
description Background and Aim: Microorganisms living in the human body play an important role in human health. Human microbiota is known as an essential agent and playing an important role in the biological processes of the human body. The role of the microbiota in the host metabolism, intestinal inflammatory responses and their treatment has been well recognized. In this study we investigated the relationship between intestinal microbiota and schizophrenia. Materials and Methods: Using keywords of”Gut microbiota”، “Schizophrenia”، “Fecal transplantation” و “Mental disorders”, we searched data bases of  SCOPUS، PubMed و Web of Science in order to find studies on the effects and relationship of the gut microbiota with occurrence of some diseases, the gut-brain relationship, and the role of fecal transplantation in the treatment of inflammatory bowel diseases and mental illnesses, particularly schizophrenia. Results: Recent studies have emphasized the importance of the microbial gut-brain axis. The intestinal microbiota has certain impacts in the process of development of mental disorders such as anxiety, stress, depression, and behavioral disorders. Conclusion: Use of gut microbiota maybe helpful for the patients with schizophrenia for improvement of the cognitive changes. In addition, due to the low prevalence and high rate of complications of this disease, more studies on the role of fecal microbiota transplantation in the patients with schizophrenia are recommended.
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spelling doaj.art-c4b377792a694f8a870aef9dee8ff1582023-09-12T10:34:40ZfasKurdistan University of Medical Sciencesمجله علمی دانشگاه علوم پزشکی کردستان1560-652X2345-40402023-05-0128298109Gut microbiome and its association with psychiatric disorders, specially schizophreniaFaria Hasanzadeh Haghighi0Bamdad Riahi-Zanjani1Ehsan Aryan2 Ph.D. Candidate, Department of Microbiology and Virology, Antimicrobial Resistance Research Center, Mashhad University of Medical Sciences, Mashhad, Iran Associate Professor, Department of Clinical Toxicology and Poisonings, Medical Toxicology Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran Associate Professor, Department of Microbiology and Virology, Antimicrobial Resistance Research Center, Mashhad University of Medical Sciences, Mashhad, Iran Background and Aim: Microorganisms living in the human body play an important role in human health. Human microbiota is known as an essential agent and playing an important role in the biological processes of the human body. The role of the microbiota in the host metabolism, intestinal inflammatory responses and their treatment has been well recognized. In this study we investigated the relationship between intestinal microbiota and schizophrenia. Materials and Methods: Using keywords of”Gut microbiota”، “Schizophrenia”، “Fecal transplantation” و “Mental disorders”, we searched data bases of  SCOPUS، PubMed و Web of Science in order to find studies on the effects and relationship of the gut microbiota with occurrence of some diseases, the gut-brain relationship, and the role of fecal transplantation in the treatment of inflammatory bowel diseases and mental illnesses, particularly schizophrenia. Results: Recent studies have emphasized the importance of the microbial gut-brain axis. The intestinal microbiota has certain impacts in the process of development of mental disorders such as anxiety, stress, depression, and behavioral disorders. Conclusion: Use of gut microbiota maybe helpful for the patients with schizophrenia for improvement of the cognitive changes. In addition, due to the low prevalence and high rate of complications of this disease, more studies on the role of fecal microbiota transplantation in the patients with schizophrenia are recommended.http://sjku.muk.ac.ir/article-1-7929-en.pdfschizophreniagut microbiotafecal transplantationmental disorders
spellingShingle Faria Hasanzadeh Haghighi
Bamdad Riahi-Zanjani
Ehsan Aryan
Gut microbiome and its association with psychiatric disorders, specially schizophrenia
مجله علمی دانشگاه علوم پزشکی کردستان
schizophrenia
gut microbiota
fecal transplantation
mental disorders
title Gut microbiome and its association with psychiatric disorders, specially schizophrenia
title_full Gut microbiome and its association with psychiatric disorders, specially schizophrenia
title_fullStr Gut microbiome and its association with psychiatric disorders, specially schizophrenia
title_full_unstemmed Gut microbiome and its association with psychiatric disorders, specially schizophrenia
title_short Gut microbiome and its association with psychiatric disorders, specially schizophrenia
title_sort gut microbiome and its association with psychiatric disorders specially schizophrenia
topic schizophrenia
gut microbiota
fecal transplantation
mental disorders
url http://sjku.muk.ac.ir/article-1-7929-en.pdf
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AT ehsanaryan gutmicrobiomeanditsassociationwithpsychiatricdisordersspeciallyschizophrenia