A phenotypic screen of the Global Health Priority Box identifies an insecticide with anthelmintic activity

A phenotypic screen of the Global Health Priority Box identifies an insecticide with anthelmintic activity

Abstract Background Infection with parasitic nematodes (helminths), particularly those of the order Strongylida (such as Haemonchus contortus), can cause significant and burdensome diseases in humans and animals. Widespread drug (anthelmintic) resistance in livestock parasites, the absence of vaccin...

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Bibliographic Details
Main Authors: Harrison T. Shanley, Aya C. Taki, Joseph J. Byrne, Nghi Nguyen, Tim N. C. Wells, Abdul Jabbar, Brad E. Sleebs, Robin B. Gasser
Format: Article
Language:English
Published: BMC 2024-03-01
Series:Parasites & Vectors
Subjects:
Anthelmintics
Drug discovery
Nematodes
Antiparasitics
Phenotypic screening
Haemonchus contortus
Online Access:https://doi.org/10.1186/s13071-024-06183-y

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