Modified Tacrine Derivatives as Multitarget-Directed Ligands for the Treatment of Alzheimer’s Disease: Synthesis, Biological Evaluation, and Molecular Modeling Study
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
American Chemical Society
2023-07-01
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| Series: | ACS Omega |
| Online Access: | https://doi.org/10.1021/acsomega.3c02051 |
| _version_ | 1797773033150087168 |
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| author | Salma Fares Walaa M. El Husseiny Khalid B. Selim Mohammed A. M. Massoud |
| author_facet | Salma Fares Walaa M. El Husseiny Khalid B. Selim Mohammed A. M. Massoud |
| author_sort | Salma Fares |
| collection | DOAJ |
| first_indexed | 2024-03-12T22:00:24Z |
| format | Article |
| id | doaj.art-c4b8071db7214f3fbbfb572e371e71a0 |
| institution | Directory Open Access Journal |
| issn | 2470-1343 |
| language | English |
| last_indexed | 2024-03-12T22:00:24Z |
| publishDate | 2023-07-01 |
| publisher | American Chemical Society |
| record_format | Article |
| series | ACS Omega |
| spelling | doaj.art-c4b8071db7214f3fbbfb572e371e71a02023-07-25T08:54:55ZengAmerican Chemical SocietyACS Omega2470-13432023-07-01829260122603410.1021/acsomega.3c02051Modified Tacrine Derivatives as Multitarget-Directed Ligands for the Treatment of Alzheimer’s Disease: Synthesis, Biological Evaluation, and Molecular Modeling StudySalma Fares0Walaa M. El Husseiny1Khalid B. Selim2Mohammed A. M. Massoud3Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Mansoura University, Mansoura, EgyptDepartment of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Mansoura University, Mansoura, EgyptDepartment of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Mansoura University, Mansoura, EgyptDepartment of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Mansoura University, Mansoura, Egypthttps://doi.org/10.1021/acsomega.3c02051 |
| spellingShingle | Salma Fares Walaa M. El Husseiny Khalid B. Selim Mohammed A. M. Massoud Modified Tacrine Derivatives as Multitarget-Directed Ligands for the Treatment of Alzheimer’s Disease: Synthesis, Biological Evaluation, and Molecular Modeling Study ACS Omega |
| title | Modified Tacrine Derivatives as Multitarget-Directed Ligands for the Treatment of Alzheimer’s Disease: Synthesis, Biological Evaluation, and Molecular Modeling Study |
| title_full | Modified Tacrine Derivatives as Multitarget-Directed Ligands for the Treatment of Alzheimer’s Disease: Synthesis, Biological Evaluation, and Molecular Modeling Study |
| title_fullStr | Modified Tacrine Derivatives as Multitarget-Directed Ligands for the Treatment of Alzheimer’s Disease: Synthesis, Biological Evaluation, and Molecular Modeling Study |
| title_full_unstemmed | Modified Tacrine Derivatives as Multitarget-Directed Ligands for the Treatment of Alzheimer’s Disease: Synthesis, Biological Evaluation, and Molecular Modeling Study |
| title_short | Modified Tacrine Derivatives as Multitarget-Directed Ligands for the Treatment of Alzheimer’s Disease: Synthesis, Biological Evaluation, and Molecular Modeling Study |
| title_sort | modified tacrine derivatives as multitarget directed ligands for the treatment of alzheimer s disease synthesis biological evaluation and molecular modeling study |
| url | https://doi.org/10.1021/acsomega.3c02051 |
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