Network Pharmacology-Based Investigation and Experimental Exploration of the Antiapoptotic Mechanism of Colchicine on Myocardial Ischemia Reperfusion Injury

Network Pharmacology-Based Investigation and Experimental Exploration of the Antiapoptotic Mechanism of Colchicine on Myocardial Ischemia Reperfusion Injury

Background: The beneficial effects of colchicine on cardiovascular disease have been widely reported in recent studies. Previous research demonstrated that colchicine has a certain protective effect on ischemic myocardium and has the potential to treat myocardial ischemia reperfusion injury (MIRI)....

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Bibliographic Details
Main Authors: Yuanjun Tang, Chenyang Shi, Yingyi Qin, Shuowen Wang, Hui Pan, Ming Chen, Xuemei Yu, Yuefen Lou, Guorong Fan
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-12-01
Series:Frontiers in Pharmacology
Subjects:
colchicine
myocardial ischemia reperfusion injury
network pharmacology
experimental verification
apoptosis
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.804030/full

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