Enzymatic co-crosslinking of star-shaped poly(ethylene glycol) tyramine and hyaluronic acid tyramine conjugates provides elastic biocompatible and biodegradable hydrogels

A combination of the viscoelastic properties of hyaluronic acid (HA) and the elastic properties of star shaped 8-arm poly(ethylene glycol) (8-arm PEG) was used to design in-situ forming hydrogels. Hydrogels were prepared by the enzymatic crosslinking of a partially tyramine modified 8-arm PEG and a...

Full description

Bibliographic Details
Main Authors: Rong Wang, Xiaobin Huang, Bram Zoetebier, Pieter J. Dijkstra, Marcel Karperien
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2023-02-01
Series:Bioactive Materials
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X22002419