Platelet dysfunction in thrombosis patients treated with vitamin K antagonists and recurrent bleeding.

Platelet dysfunction in thrombosis patients treated with vitamin K antagonists and recurrent bleeding.

BACKGROUND: Recurrent bleeding can complicate the treatment of thrombosis patients with vitamin K antagonists (VKA), even at a well-regulated level of anticoagulation. In this proof-of-principle study, we investigated whether alterations in platelet function or von Willebrand factor (vWf) contribute...

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Main Authors: Paola E J van der Meijden, Annemieke C Bouman, Marion A H Feijge, René van Oerle, Henri M H Spronk, Karly Hamulyák, Arina J ten Cate-Hoek, Hugo ten Cate, Johan W M Heemskerk
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3665853?pdf=render

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