Meta-populational demes constitute a reservoir for large MHC allele diversity in wild house mice (Mus musculus)
Abstract Background The MHC class I and II loci mediate the adaptive immune response and belong to the most polymorphic loci in vertebrate genomes. In fact, the number of different alleles in a given species is often so large that it remains a challenge to provide an evolutionary model that can full...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2018-04-01
|
| Series: | Frontiers in Zoology |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s12983-018-0266-9 |