An Extremely Rare Case of Granular Cell Tumour of Right Nasal Vestibule
Granular Cell Tumour (GCT) of nasal and paranasal area is an extremely rare entity, while the most common site is the tongue in oral cavity. GCT was first time described by Abrikossoff in 1926, which occurs in 3rd to 5th decades of life and most frequently involving the head and neck region. Abrikos...
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| Format: | Article |
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JCDR Research and Publications Private Limited
2022-02-01
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| Series: | Journal of Clinical and Diagnostic Research |
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| Online Access: | https://www.jcdr.net/articles/PDF/16021/52671_CE(Ra1)_F(SS)_PF1(JY_SS)_PFA(JY_KM)_PN(KM).pdf |
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| author | Pooja Agarwal Nupur Kaushik Lalit Kumar Akhil Pratap Singh |
| author_facet | Pooja Agarwal Nupur Kaushik Lalit Kumar Akhil Pratap Singh |
| author_sort | Pooja Agarwal |
| collection | DOAJ |
| description | Granular Cell Tumour (GCT) of nasal and paranasal area is an extremely rare entity, while the most common site is the tongue in oral cavity. GCT was first time described by Abrikossoff in 1926, which occurs in 3rd to 5th decades of life and most frequently involving the head and neck region. Abrikossoff in 1926, first time described GCT, to be derived from smooth muscle and gave the term myoblastomas, also known as Abrikossoff’s tumours. Schwann cell origin of GCT was demonstrated on immunohistochemistry through positive S100 protein identification. Herein, the authors report a case of GCT arising from right nasal vestibule in a 28-year-old female who presented with swelling since three months. On gross examination, the specimen revealed firm red and white pieces of tissue measuring 0.8x0.8x0.5 cm. Diagnosis was made by histopathological examination which was confirmed by PAS special stain and S100 immunohistochemistry. Author also abridged the clinical information, microscopic features, treatment and patient status after follow-up. This case is believed to be the 7th reported case of GCT as primary lesion at this location. |
| first_indexed | 2024-04-10T17:26:19Z |
| format | Article |
| id | doaj.art-c4c094290707417bb468953920ddf244 |
| institution | Directory Open Access Journal |
| issn | 2249-782X 0973-709X |
| language | English |
| last_indexed | 2024-04-10T17:26:19Z |
| publishDate | 2022-02-01 |
| publisher | JCDR Research and Publications Private Limited |
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| series | Journal of Clinical and Diagnostic Research |
| spelling | doaj.art-c4c094290707417bb468953920ddf2442023-02-04T05:54:08ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2022-02-01162ED04ED0510.7860/JCDR/2022/52671.16021An Extremely Rare Case of Granular Cell Tumour of Right Nasal VestibulePooja Agarwal0Nupur Kaushik1Lalit Kumar2Akhil Pratap Singh3Professor, Department of Pathology, Sarojini Naidu Medical College, Agra, Uttar Pradesh, India.Senior Resident, Department of Pathology, Sarojini Naidu Medical College, Agra, Uttar Pradesh, India.Senior Resident, Department of Pathology, Sarojini Naidu Medical College, Agra, Uttar Pradesh, India.Assistant Professor, Department of Ear, Nose and Throat, Sarojini Naidu Medical College, Agra, Uttar Pradesh, India.Granular Cell Tumour (GCT) of nasal and paranasal area is an extremely rare entity, while the most common site is the tongue in oral cavity. GCT was first time described by Abrikossoff in 1926, which occurs in 3rd to 5th decades of life and most frequently involving the head and neck region. Abrikossoff in 1926, first time described GCT, to be derived from smooth muscle and gave the term myoblastomas, also known as Abrikossoff’s tumours. Schwann cell origin of GCT was demonstrated on immunohistochemistry through positive S100 protein identification. Herein, the authors report a case of GCT arising from right nasal vestibule in a 28-year-old female who presented with swelling since three months. On gross examination, the specimen revealed firm red and white pieces of tissue measuring 0.8x0.8x0.5 cm. Diagnosis was made by histopathological examination which was confirmed by PAS special stain and S100 immunohistochemistry. Author also abridged the clinical information, microscopic features, treatment and patient status after follow-up. This case is believed to be the 7th reported case of GCT as primary lesion at this location.https://www.jcdr.net/articles/PDF/16021/52671_CE(Ra1)_F(SS)_PF1(JY_SS)_PFA(JY_KM)_PN(KM).pdfmyoblastomaspremalignants100sphingomyelin |
| spellingShingle | Pooja Agarwal Nupur Kaushik Lalit Kumar Akhil Pratap Singh An Extremely Rare Case of Granular Cell Tumour of Right Nasal Vestibule Journal of Clinical and Diagnostic Research myoblastomas premalignant s100 sphingomyelin |
| title | An Extremely Rare Case of Granular Cell Tumour of Right Nasal Vestibule |
| title_full | An Extremely Rare Case of Granular Cell Tumour of Right Nasal Vestibule |
| title_fullStr | An Extremely Rare Case of Granular Cell Tumour of Right Nasal Vestibule |
| title_full_unstemmed | An Extremely Rare Case of Granular Cell Tumour of Right Nasal Vestibule |
| title_short | An Extremely Rare Case of Granular Cell Tumour of Right Nasal Vestibule |
| title_sort | extremely rare case of granular cell tumour of right nasal vestibule |
| topic | myoblastomas premalignant s100 sphingomyelin |
| url | https://www.jcdr.net/articles/PDF/16021/52671_CE(Ra1)_F(SS)_PF1(JY_SS)_PFA(JY_KM)_PN(KM).pdf |
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