Ulcerations due to methotrexate toxicity in a psoriasis patient
Abstract: Methotrexate is one of the most used drugs in the treatment of psoriasis with indication of systemic therapy. Cutaneous and mucous side effects are described by pharmacological characteristics of the drug itself or due to overdose. We report the case of a patient with ulcerations in oral m...
Main Authors: | , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Sociedade Brasileira de Dermatologia
2016-06-01
|
Series: | Anais Brasileiros de Dermatologia |
Subjects: | |
Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962016000300375&tlng=en |
_version_ | 1819284084670595072 |
---|---|
author | Claudia Fernanda Dias Souza Olga Milena Zarco Suarez Talita Fonseca Medeiros da Silva Ana Carolina Lourenço Araújo Gorenstein Leonardo Pereira Quintella João Carlos Regazzi Avelleira |
author_facet | Claudia Fernanda Dias Souza Olga Milena Zarco Suarez Talita Fonseca Medeiros da Silva Ana Carolina Lourenço Araújo Gorenstein Leonardo Pereira Quintella João Carlos Regazzi Avelleira |
author_sort | Claudia Fernanda Dias Souza |
collection | DOAJ |
description | Abstract: Methotrexate is one of the most used drugs in the treatment of psoriasis with indication of systemic therapy. Cutaneous and mucous side effects are described by pharmacological characteristics of the drug itself or due to overdose. We report the case of a patient with ulcerations in oral mucosa and psoriatic plaques after incorrect use of Methotrexate. Prescribed in a weekly dose, it was used continuously for 10 days and without simultaneous intake of folic acid. It is important to ensure correct comprehension of the prescription. |
first_indexed | 2024-12-24T01:41:45Z |
format | Article |
id | doaj.art-c4c14683861041a1ba583ea04e71bee6 |
institution | Directory Open Access Journal |
issn | 0365-0596 |
language | English |
last_indexed | 2024-12-24T01:41:45Z |
publishDate | 2016-06-01 |
publisher | Sociedade Brasileira de Dermatologia |
record_format | Article |
series | Anais Brasileiros de Dermatologia |
spelling | doaj.art-c4c14683861041a1ba583ea04e71bee62022-12-21T17:22:01ZengSociedade Brasileira de DermatologiaAnais Brasileiros de Dermatologia0365-05962016-06-0191337537710.1590/abd1806-4841.20163960Ulcerations due to methotrexate toxicity in a psoriasis patientClaudia Fernanda Dias SouzaOlga Milena Zarco SuarezTalita Fonseca Medeiros da SilvaAna Carolina Lourenço Araújo GorensteinLeonardo Pereira QuintellaJoão Carlos Regazzi AvelleiraAbstract: Methotrexate is one of the most used drugs in the treatment of psoriasis with indication of systemic therapy. Cutaneous and mucous side effects are described by pharmacological characteristics of the drug itself or due to overdose. We report the case of a patient with ulcerations in oral mucosa and psoriatic plaques after incorrect use of Methotrexate. Prescribed in a weekly dose, it was used continuously for 10 days and without simultaneous intake of folic acid. It is important to ensure correct comprehension of the prescription.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962016000300375&tlng=enMethotrexatePsoriasisTherapeuticsToxicity |
spellingShingle | Claudia Fernanda Dias Souza Olga Milena Zarco Suarez Talita Fonseca Medeiros da Silva Ana Carolina Lourenço Araújo Gorenstein Leonardo Pereira Quintella João Carlos Regazzi Avelleira Ulcerations due to methotrexate toxicity in a psoriasis patient Anais Brasileiros de Dermatologia Methotrexate Psoriasis Therapeutics Toxicity |
title | Ulcerations due to methotrexate toxicity in a psoriasis patient |
title_full | Ulcerations due to methotrexate toxicity in a psoriasis patient |
title_fullStr | Ulcerations due to methotrexate toxicity in a psoriasis patient |
title_full_unstemmed | Ulcerations due to methotrexate toxicity in a psoriasis patient |
title_short | Ulcerations due to methotrexate toxicity in a psoriasis patient |
title_sort | ulcerations due to methotrexate toxicity in a psoriasis patient |
topic | Methotrexate Psoriasis Therapeutics Toxicity |
url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962016000300375&tlng=en |
work_keys_str_mv | AT claudiafernandadiassouza ulcerationsduetomethotrexatetoxicityinapsoriasispatient AT olgamilenazarcosuarez ulcerationsduetomethotrexatetoxicityinapsoriasispatient AT talitafonsecamedeirosdasilva ulcerationsduetomethotrexatetoxicityinapsoriasispatient AT anacarolinalourencoaraujogorenstein ulcerationsduetomethotrexatetoxicityinapsoriasispatient AT leonardopereiraquintella ulcerationsduetomethotrexatetoxicityinapsoriasispatient AT joaocarlosregazziavelleira ulcerationsduetomethotrexatetoxicityinapsoriasispatient |