Porphyromonas gingivalis promotes malignancy and chemo-resistance via GSK3β-mediated mitochondrial oxidative phosphorylation in human esophageal squamous cell carcinoma

Porphyromonas gingivalis promotes malignancy and chemo-resistance via GSK3β-mediated mitochondrial oxidative phosphorylation in human esophageal squamous cell carcinoma

Our prior studies have confirmed that long-term colonization of Porphyromonas gingivalis (Pg) and overexpression of the inflammatory factor glycogen synthase kinase 3β (GSK3β) promote the malignant evolution of esophageal squamous cell carcinoma (ESCC). We aimed to investigate the functional mechani...

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Bibliographic Details
Main Authors: Yiwen Liu, Fuyou Zhou, Haijun Yang, Zheyuan Zhang, Jiahao Zhang, Keyao He, Mengfan Qian, Ruonan Li, Wei Sun, Ningtao Dai, Junkuo Li, Yibo Guo, Jinyu Kong, Shegan Gao
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:Translational Oncology
Subjects:
Porphyromonas gingivalis
Glycogen synthase kinase 3β
Mitochondrial oxidative phosphorylation
Chemo-resistance
Malignancy
Postoperative survival
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523323000426

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http://www.sciencedirect.com/science/article/pii/S1936523323000426

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